Hemoperitoneum secondary to rupture of a hepatic metastasis from small cell lung cancer during chemotherapy: A case with a literature review

Takao Mochimaru; Naoto Minematsu; Kazuma Ohsawa; Katsuyoshi Tomomatsu; Hiroshi Miura; Tomoko Betsuyaku; Marohito Murakami

doi:10.2169/internalmedicine.56.6828

Hemoperitoneum secondary to rupture of a hepatic metastasis from small cell lung cancer during chemotherapy: A case with a literature review

Takao Mochimaru, Naoto Minematsu, Kazuma Ohsawa, Katsuyoshi Tomomatsu, Hiroshi Miura, Tomoko Betsuyaku, Marohito Murakami

Research output: Contribution to journal › Review article › peer-review

11 Citations (Scopus)

Abstract

A 65-year-old man was diagnosed with small cell lung cancer with multiple liver metastases. Three days after initiating chemotherapy, he experienced abdominal discomfort with hypotension. Computed tomography revealed a ruptured liver metastasis and the presence of hemorrhagic ascites. Transcatheter arterial embolization to the appropriate hepatic artery in concomitant with supportive therapies successfully stabilized his condition. Unlike with hepatocellular carcinoma, the rupture of a liver metastasis and associated hemoperitoneum is very rare in patients with lung cancer. We comprehensively reviewed the literature and found 10 similar cases with this serious condition. Physicians should therefore be aware of the risk of hemoperitoneum caused by ruptured liver metastases in patients with lung cancer.

Original language	English
Pages (from-to)	695-699
Number of pages	5
Journal	Internal Medicine
Volume	56
Issue number	6
DOIs	https://doi.org/10.2169/internalmedicine.56.6828
Publication status	Published - 2017

Keywords

Chemotherapy
Hemoperitoneum
Hepatic metastasis
Lung cancer
Transcatheter arterial embolization

ASJC Scopus subject areas

Internal Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.2169/internalmedicine.56.6828

Cite this

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title = "Hemoperitoneum secondary to rupture of a hepatic metastasis from small cell lung cancer during chemotherapy: A case with a literature review",

abstract = "A 65-year-old man was diagnosed with small cell lung cancer with multiple liver metastases. Three days after initiating chemotherapy, he experienced abdominal discomfort with hypotension. Computed tomography revealed a ruptured liver metastasis and the presence of hemorrhagic ascites. Transcatheter arterial embolization to the appropriate hepatic artery in concomitant with supportive therapies successfully stabilized his condition. Unlike with hepatocellular carcinoma, the rupture of a liver metastasis and associated hemoperitoneum is very rare in patients with lung cancer. We comprehensively reviewed the literature and found 10 similar cases with this serious condition. Physicians should therefore be aware of the risk of hemoperitoneum caused by ruptured liver metastases in patients with lung cancer.",

keywords = "Chemotherapy, Hemoperitoneum, Hepatic metastasis, Lung cancer, Transcatheter arterial embolization",

author = "Takao Mochimaru and Naoto Minematsu and Kazuma Ohsawa and Katsuyoshi Tomomatsu and Hiroshi Miura and Tomoko Betsuyaku and Marohito Murakami",

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T1 - Hemoperitoneum secondary to rupture of a hepatic metastasis from small cell lung cancer during chemotherapy

T2 - A case with a literature review

AU - Mochimaru, Takao

AU - Minematsu, Naoto

AU - Ohsawa, Kazuma

AU - Tomomatsu, Katsuyoshi

AU - Miura, Hiroshi

AU - Betsuyaku, Tomoko

AU - Murakami, Marohito

PY - 2017

Y1 - 2017

N2 - A 65-year-old man was diagnosed with small cell lung cancer with multiple liver metastases. Three days after initiating chemotherapy, he experienced abdominal discomfort with hypotension. Computed tomography revealed a ruptured liver metastasis and the presence of hemorrhagic ascites. Transcatheter arterial embolization to the appropriate hepatic artery in concomitant with supportive therapies successfully stabilized his condition. Unlike with hepatocellular carcinoma, the rupture of a liver metastasis and associated hemoperitoneum is very rare in patients with lung cancer. We comprehensively reviewed the literature and found 10 similar cases with this serious condition. Physicians should therefore be aware of the risk of hemoperitoneum caused by ruptured liver metastases in patients with lung cancer.

AB - A 65-year-old man was diagnosed with small cell lung cancer with multiple liver metastases. Three days after initiating chemotherapy, he experienced abdominal discomfort with hypotension. Computed tomography revealed a ruptured liver metastasis and the presence of hemorrhagic ascites. Transcatheter arterial embolization to the appropriate hepatic artery in concomitant with supportive therapies successfully stabilized his condition. Unlike with hepatocellular carcinoma, the rupture of a liver metastasis and associated hemoperitoneum is very rare in patients with lung cancer. We comprehensively reviewed the literature and found 10 similar cases with this serious condition. Physicians should therefore be aware of the risk of hemoperitoneum caused by ruptured liver metastases in patients with lung cancer.

KW - Chemotherapy

KW - Hemoperitoneum

KW - Hepatic metastasis

KW - Lung cancer

KW - Transcatheter arterial embolization

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Hemoperitoneum secondary to rupture of a hepatic metastasis from small cell lung cancer during chemotherapy: A case with a literature review

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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