Hidden depression in otolaryngology patients with medically unexplained symptoms

Fumiyuki Goto, Tomoko Tsutsumi, Naoki Oishi, Masaru Mimura

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


Objective: To investigate the prevalence of depression among otolaryngology patients with medically unexplained symptoms (MUS) and the outcome of treatment with selective serotonin reuptake inhibitors (SSRIs). Method: Ninety patients with MUS from a population of 983 consecutive otolaryngology outpatients were enrolled. The Self-Rating Depression Scale (SDS) was used to screen for depression. In addition to standard treatment, all depressed and nondepressed patients received SSRIs for 8 weeks. The Clinical Global Impression-Improvement (CGI-I) scale was used to evaluate clinical changes in patients with MUS. Results: There were 49 patients with depression among those with MUS, according to the SDS criteria. The patients with depression showed a better outcome than those without depression, demonstrating more significantly improved CGI-I scores. Conclusion: More than half of the individuals with otolaryngological MUS had depression, and their MUS were successfully treated withSSRIs.

Original languageEnglish
Pages (from-to)206-208
Number of pages3
JournalGeneral Hospital Psychiatry
Issue number2
Publication statusPublished - 2012 Mar


  • Antidepressant
  • Depression
  • Medically unexplained symptoms
  • Selective serotonin reuptake inhibitors

ASJC Scopus subject areas

  • Psychiatry and Mental health


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