TY - JOUR
T1 - High-performance liquid chromatography of anti-pyretics on chemically modified porous glass
AU - Matsushima, Yoshikazu
AU - Nagata, Yoshiko
AU - Takakusagi, Keiko
AU - Niyomura, Miki
AU - Takai, Nobuharu
PY - 1985/9/20
Y1 - 1985/9/20
N2 - An octadecylsilyl porous glass was prepared and used as the packing for reversed-phase high-performance liquid chromatography. Five antipyretic drugs (aspirin, caffeine, guaiacol glycerol ether, 3-hydroxy-p-butyrophenetidine, and phenacetin) were separated in 2 min with a mobile phase of 20% acetonitrile at a flow-rate of 3.0 ml/min. A pharmaceutical preparation, containing aspirin, phenacetin, caffeine and chlorpheniramine maleate was analysed in 2 min with a mobile phase of acetonitrile-water-acetic acid (20:79:1). The packing seems promising for the rapid analysis of pharmaceuticals and biomedical compounds.
AB - An octadecylsilyl porous glass was prepared and used as the packing for reversed-phase high-performance liquid chromatography. Five antipyretic drugs (aspirin, caffeine, guaiacol glycerol ether, 3-hydroxy-p-butyrophenetidine, and phenacetin) were separated in 2 min with a mobile phase of 20% acetonitrile at a flow-rate of 3.0 ml/min. A pharmaceutical preparation, containing aspirin, phenacetin, caffeine and chlorpheniramine maleate was analysed in 2 min with a mobile phase of acetonitrile-water-acetic acid (20:79:1). The packing seems promising for the rapid analysis of pharmaceuticals and biomedical compounds.
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U2 - 10.1016/S0021-9673(01)83305-7
DO - 10.1016/S0021-9673(01)83305-7
M3 - Article
C2 - 3877070
AN - SCOPUS:0021891272
SN - 0021-9673
VL - 332
SP - 265
EP - 268
JO - Journal of Chromatography A
JF - Journal of Chromatography A
IS - C
ER -