High Solubility of Random-Sequence Proteins Consisting of Five Kinds of Primitive Amino Acids

Nobuhide Doi, Koichi Kakukawa, Yuko Oishi, Hiroshi Yanagawa

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)
Original languageEnglish
Title of host publicationChemical Synthetic Biology
PublisherJohn Wiley and Sons
Number of pages19
ISBN (Print)9780470713976
Publication statusPublished - 2011 Feb 14


  • CD and fluorescence measurements
  • DNA library construction-of random-sequence proteins
  • DNA library, cloned and sequenced-with ABI PRISM 3100 (Applied Biosystems)
  • Design of DNAs encoding random-sequence proteins-and primitive alphabets
  • Peptides and proteins-high solubility of random-sequence proteins
  • Searching for functional proteins, and random-sequence libraries-major challenges
  • Size-exclusion chromatography
  • Structural characterization of VADEG proteins
  • Universal genetic code and amino acid abundance-in simulated prebiotic synthesis

ASJC Scopus subject areas

  • General Biochemistry,Genetics and Molecular Biology

Cite this