Highly efficient hydroxylation of gaseous alkanes at reduced temperature catalyzed by cytochrome P450BM3 assisted by decoy molecules

Norifumi Kawakami; Zhiqi Cong; Osami Shoji; Yoshihito Watanabe

doi:10.1142/S1088424615500145

Highly efficient hydroxylation of gaseous alkanes at reduced temperature catalyzed by cytochrome P450BM3 assisted by decoy molecules

Norifumi Kawakami, Zhiqi Cong, Osami Shoji, Yoshihito Watanabe

Department of Biosciences and Informatics

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Cytochrome P450BM3 functions as a small-alkane hydroxylase upon the addition of perfluorocarboxylic acids (PFs) as decoy molecules. The coupling efficiency (product formation rate per NADPH consumption rate) for the hydroxylation of small alkanes was improved by reducing the reaction temperature to 0°C.

Original language	English
Pages (from-to)	329-334
Number of pages	6
Journal	Journal of Porphyrins and Phthalocyanines
Volume	19
Issue number	1-3
DOIs	https://doi.org/10.1142/S1088424615500145
Publication status	Published - 2015 Jan 1

Keywords

cytochrome P450
decoy molecules
gaseous alkanes
perfluorocarboxylic acids

ASJC Scopus subject areas

Chemistry(all)

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10.1142/S1088424615500145

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abstract = "Cytochrome P450BM3 functions as a small-alkane hydroxylase upon the addition of perfluorocarboxylic acids (PFs) as decoy molecules. The coupling efficiency (product formation rate per NADPH consumption rate) for the hydroxylation of small alkanes was improved by reducing the reaction temperature to 0°C.",

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AU - Kawakami, Norifumi

AU - Cong, Zhiqi

AU - Shoji, Osami

AU - Watanabe, Yoshihito

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Cytochrome P450BM3 functions as a small-alkane hydroxylase upon the addition of perfluorocarboxylic acids (PFs) as decoy molecules. The coupling efficiency (product formation rate per NADPH consumption rate) for the hydroxylation of small alkanes was improved by reducing the reaction temperature to 0°C.

AB - Cytochrome P450BM3 functions as a small-alkane hydroxylase upon the addition of perfluorocarboxylic acids (PFs) as decoy molecules. The coupling efficiency (product formation rate per NADPH consumption rate) for the hydroxylation of small alkanes was improved by reducing the reaction temperature to 0°C.

KW - cytochrome P450

KW - decoy molecules

KW - gaseous alkanes

KW - perfluorocarboxylic acids

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ER -

Highly efficient hydroxylation of gaseous alkanes at reduced temperature catalyzed by cytochrome P450BM3 assisted by decoy molecules

Abstract

Keywords

ASJC Scopus subject areas

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