Highly efficient hydroxylation of gaseous alkanes at reduced temperature catalyzed by cytochrome P450BM3 assisted by decoy molecules

Norifumi Kawakami; Zhiqi Cong; Osami Shoji; Yoshihito Watanabe

doi:10.1142/S1088424615500145

Highly efficient hydroxylation of gaseous alkanes at reduced temperature catalyzed by cytochrome P450BM3 assisted by decoy molecules

Norifumi Kawakami
, Zhiqi Cong
, Osami Shoji
, Yoshihito Watanabe

Department of Biosciences and Informatics

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

Cytochrome P450BM3 functions as a small-alkane hydroxylase upon the addition of perfluorocarboxylic acids (PFs) as decoy molecules. The coupling efficiency (product formation rate per NADPH consumption rate) for the hydroxylation of small alkanes was improved by reducing the reaction temperature to 0°C.

Original language	English
Pages (from-to)	329-334
Number of pages	6
Journal	Journal of Porphyrins and Phthalocyanines
Volume	19
Issue number	1-3
DOIs	https://doi.org/10.1142/S1088424615500145
Publication status	Published - 2015 Jan 1

Keywords

cytochrome P450
decoy molecules
gaseous alkanes
perfluorocarboxylic acids

ASJC Scopus subject areas

General Chemistry

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10.1142/S1088424615500145

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title = "Highly efficient hydroxylation of gaseous alkanes at reduced temperature catalyzed by cytochrome P450BM3 assisted by decoy molecules",

abstract = "Cytochrome P450BM3 functions as a small-alkane hydroxylase upon the addition of perfluorocarboxylic acids (PFs) as decoy molecules. The coupling efficiency (product formation rate per NADPH consumption rate) for the hydroxylation of small alkanes was improved by reducing the reaction temperature to 0°C.",

keywords = "cytochrome P450, decoy molecules, gaseous alkanes, perfluorocarboxylic acids",

author = "Norifumi Kawakami and Zhiqi Cong and Osami Shoji and Yoshihito Watanabe",

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T1 - Highly efficient hydroxylation of gaseous alkanes at reduced temperature catalyzed by cytochrome P450BM3 assisted by decoy molecules

AU - Kawakami, Norifumi

AU - Cong, Zhiqi

AU - Shoji, Osami

AU - Watanabe, Yoshihito

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Cytochrome P450BM3 functions as a small-alkane hydroxylase upon the addition of perfluorocarboxylic acids (PFs) as decoy molecules. The coupling efficiency (product formation rate per NADPH consumption rate) for the hydroxylation of small alkanes was improved by reducing the reaction temperature to 0°C.

AB - Cytochrome P450BM3 functions as a small-alkane hydroxylase upon the addition of perfluorocarboxylic acids (PFs) as decoy molecules. The coupling efficiency (product formation rate per NADPH consumption rate) for the hydroxylation of small alkanes was improved by reducing the reaction temperature to 0°C.

KW - cytochrome P450

KW - decoy molecules

KW - gaseous alkanes

KW - perfluorocarboxylic acids

UR - https://www.scopus.com/pages/publications/85027945300

UR - https://www.scopus.com/pages/publications/85027945300#tab=citedBy

U2 - 10.1142/S1088424615500145

DO - 10.1142/S1088424615500145

M3 - Article

AN - SCOPUS:85027945300

SN - 1088-4246

VL - 19

SP - 329

EP - 334

JO - Journal of Porphyrins and Phthalocyanines

JF - Journal of Porphyrins and Phthalocyanines

IS - 1-3

ER -

Highly efficient hydroxylation of gaseous alkanes at reduced temperature catalyzed by cytochrome P450BM3 assisted by decoy molecules

Abstract

Keywords

ASJC Scopus subject areas

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