Highly enantioselective cyclopropanation in alcoholic and aqueous solvents catalyzed by optically active β-ketoiminato cobalt(II) complex

T. Ikeno; A. Nishizuka; M. Sato; T. Yamada

doi:10.1055/s-2001-11416

Highly enantioselective cyclopropanation in alcoholic and aqueous solvents catalyzed by optically active β-ketoiminato cobalt(II) complex

T. Ikeno
, A. Nishizuka
, M. Sato
, T. Yamada

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

The highly enantioselective cyclopropanation of styrenes and diazoacetates proceeded in alcohol or aqueous alcohol in the presence of the β-ketoiminato cobalt(II) complex. Water and alcohols accelerated the reaction and improved the diastereo- and enantioselectivities. In these media, the α,α-disubstituted styrenes were smoothly cyclopropanated with high enantiomeric excess.

Original language	English
Pages (from-to)	406-408
Number of pages	3
Journal	Synlett
Issue number	3
DOIs	https://doi.org/10.1055/s-2001-11416
Publication status	Published - 2001

Keywords

Alcohols
Asymmetric synthesis
Cobalt
Cyclopropanation
Water

ASJC Scopus subject areas

Organic Chemistry

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10.1055/s-2001-11416

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title = "Highly enantioselective cyclopropanation in alcoholic and aqueous solvents catalyzed by optically active β-ketoiminato cobalt(II) complex",

abstract = "The highly enantioselective cyclopropanation of styrenes and diazoacetates proceeded in alcohol or aqueous alcohol in the presence of the β-ketoiminato cobalt(II) complex. Water and alcohols accelerated the reaction and improved the diastereo- and enantioselectivities. In these media, the α,α-disubstituted styrenes were smoothly cyclopropanated with high enantiomeric excess.",

keywords = "Alcohols, Asymmetric synthesis, Cobalt, Cyclopropanation, Water",

author = "T. Ikeno and A. Nishizuka and M. Sato and T. Yamada",

year = "2001",

doi = "10.1055/s-2001-11416",

language = "English",

pages = "406--408",

journal = "Synlett",

issn = "0936-5214",

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T1 - Highly enantioselective cyclopropanation in alcoholic and aqueous solvents catalyzed by optically active β-ketoiminato cobalt(II) complex

AU - Ikeno, T.

AU - Nishizuka, A.

AU - Sato, M.

AU - Yamada, T.

PY - 2001

Y1 - 2001

N2 - The highly enantioselective cyclopropanation of styrenes and diazoacetates proceeded in alcohol or aqueous alcohol in the presence of the β-ketoiminato cobalt(II) complex. Water and alcohols accelerated the reaction and improved the diastereo- and enantioselectivities. In these media, the α,α-disubstituted styrenes were smoothly cyclopropanated with high enantiomeric excess.

AB - The highly enantioselective cyclopropanation of styrenes and diazoacetates proceeded in alcohol or aqueous alcohol in the presence of the β-ketoiminato cobalt(II) complex. Water and alcohols accelerated the reaction and improved the diastereo- and enantioselectivities. In these media, the α,α-disubstituted styrenes were smoothly cyclopropanated with high enantiomeric excess.

KW - Alcohols

KW - Asymmetric synthesis

KW - Cobalt

KW - Cyclopropanation

KW - Water

UR - https://www.scopus.com/pages/publications/0035100362

UR - https://www.scopus.com/pages/publications/0035100362#tab=citedBy

U2 - 10.1055/s-2001-11416

DO - 10.1055/s-2001-11416

M3 - Article

AN - SCOPUS:0035100362

SN - 0936-5214

SP - 406

EP - 408

JO - Synlett

JF - Synlett

IS - 3

ER -

Highly enantioselective cyclopropanation in alcoholic and aqueous solvents catalyzed by optically active β-ketoiminato cobalt(II) complex

Abstract

Keywords

ASJC Scopus subject areas

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