TY - JOUR
T1 - Hospital meal intake in acute heart failure patients and its association with long-term outcomes
AU - Yoshida, Taizo
AU - Shoji, Satoshi
AU - Shiraishi, Yasuyuki
AU - Kawana, Masataka
AU - Kohno, Takashi
AU - Inoue, Kenji
AU - Fukuda, Keiichi
AU - Heidenreich, Paul A.
AU - Kohsaka, Shun
N1 - Funding Information:
Contributors The author contributions are as follows: Planning and conducting the research: TY, SS, YS and SK. Reporting of the work: TY, SS and YS. Critical revision of the manuscript for important intellectual content: MK, TK, KI, KF and PAH. Funding This work was supported by a grant from the Japan Agency for Medical Research and Development (201439013C (SK)), Health Labor Sciences Research Grant (14528506; (SK)), a Grant-Aid for Scientific Research (KAKENHI, 18K08056 (SK)) and a Grant-in-Aid for Young Scientists (JPSS KAKENHI, 18K15860 (YS)). Competing interests SK reports investigator-initiated grant funding from Bayer and Daiichi Sankyo. The other authors declare no conflict of interest. Patient consent for publication Not required. ethics approval The study protocol was approved by the Keio University Institutional Review Board, and the research was conducted in accordance with the Declaration of Helsinki. Provenance and peer review Not commissioned; externally peer reviewed. data availability statement Data are available on reasonable request. open access This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
Funding Information:
This work was supported by a grant from the Japan Agency for Medical Research and Development (201439013C (SK)), Health Labor Sciences Research Grant (14528506; (SK)), a Grant-Aid for Scientific Research (KAKENHI, 18K08056 (SK)) and a Grant-in- Aid for Young Scientists (JPSS KAKENHI, 18K15860 (YS)).
Publisher Copyright:
© 2020 Author(s).
PY - 2020/5/10
Y1 - 2020/5/10
N2 - Background: Risk prediction for hospitalised heart failure (HF, HHF) patients remains suboptimal. We aimed to determine the prognostic value of hospital food intake (FI) immediately before discharge among HHF patients. Method: We analysed the data of 255 HHF patients extracted from the records of a single university hospital. The FI percentage of the three meals the day before hospital discharge was averaged. Patients were stratified into adequate FI (100% consumption) and inadequate FI (less than 100% consumption) groups. The primary outcome was the composite of all-cause mortality and/or HF readmission within 1 year. Results: Only 49.3% of HHF patients consumed 100% of their meals. Patients with inadequate FI were older; predominantly women; and had a lower body mass index, higher brain natriuretic peptide levels and Clinical Frailty Scale scores at discharge than those with adequate FI. Inadequate FI was significantly associated with adverse outcomes after adjustments (HR 2.00; 95% CI 1.09 to 3.67; p=0.026). The effect of interaction by ejection fraction (EF) was highly significant: HF with preserved EF (≥40%) was significantly associated with inadequate FI with adverse outcomes (HR 4.95; 95% CI 1.71 to 14.36; p=0.003) but HF with reduced EF (<40%) was not (HR 0.77; 95% CI 0.31 to 1.95; p=0.590). Conclusions: The hospital FI assessment might be a simple, useful tool for predicting and stratifying risk for HHF patients.
AB - Background: Risk prediction for hospitalised heart failure (HF, HHF) patients remains suboptimal. We aimed to determine the prognostic value of hospital food intake (FI) immediately before discharge among HHF patients. Method: We analysed the data of 255 HHF patients extracted from the records of a single university hospital. The FI percentage of the three meals the day before hospital discharge was averaged. Patients were stratified into adequate FI (100% consumption) and inadequate FI (less than 100% consumption) groups. The primary outcome was the composite of all-cause mortality and/or HF readmission within 1 year. Results: Only 49.3% of HHF patients consumed 100% of their meals. Patients with inadequate FI were older; predominantly women; and had a lower body mass index, higher brain natriuretic peptide levels and Clinical Frailty Scale scores at discharge than those with adequate FI. Inadequate FI was significantly associated with adverse outcomes after adjustments (HR 2.00; 95% CI 1.09 to 3.67; p=0.026). The effect of interaction by ejection fraction (EF) was highly significant: HF with preserved EF (≥40%) was significantly associated with inadequate FI with adverse outcomes (HR 4.95; 95% CI 1.71 to 14.36; p=0.003) but HF with reduced EF (<40%) was not (HR 0.77; 95% CI 0.31 to 1.95; p=0.590). Conclusions: The hospital FI assessment might be a simple, useful tool for predicting and stratifying risk for HHF patients.
KW - heart failure
KW - heart failure with normal ejection fraction
KW - systolic heart failure
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U2 - 10.1136/openhrt-2020-001248
DO - 10.1136/openhrt-2020-001248
M3 - Article
AN - SCOPUS:85085134581
SN - 2398-595X
VL - 7
JO - Open Heart
JF - Open Heart
IS - 1
M1 - e001248
ER -