TY - JOUR
T1 - Impact of non-exercise activity thermogenesis on physical activity in patients with COPD
AU - Shirahata, Toru
AU - Nishida, Yuki
AU - Sato, Hideaki
AU - Yogi, Sanehiro
AU - Akagami, Tomoe
AU - Nagata, Makoto
AU - Tanaka, Shigeho
AU - Nakamura, Hidetoshi
AU - Katsukawa, Fuminori
N1 - Funding Information:
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by the Japan Agency for Medical Research and Development (grant number JP17ek0210045 and JP20ek0210112.).
Funding Information:
We thank Azusa Sasaki (National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo, Japan) and Hitoshi Miyazawa (Saitama Medical University, Saitama, Japan) for their skillful technical assistance. The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This work was supported by the Japan Agency for Medical Research and Development (grant number JP17ek0210045 and JP20ek0210112.).
Publisher Copyright:
© The Author(s) 2022.
PY - 2022/7
Y1 - 2022/7
N2 - Physical inactivity is associated with comorbidities and mortality in chronic obstructive pulmonary disease (COPD) patients. Although non-exercise activity thermogenesis (NEAT) is important for evaluating the physical activity level (PAL) of patients with chronic diseases, it has not yet been assessed in COPD patients. This study included male patients with COPD (n = 28) and high risk for COPD (n = 8). Total energy expenditure (TEE) and basal metabolic rate (BMR) were measured using the doubly labeled water (DLW) method and indirect calorimetry, respectively. PAL was calculated as TEE/BMR, while the NEAT was obtained from a questionnaire. Physical activity was also assessed using an accelerometer. The total NEAT score was correlated with PAL (r = 0.534, P < 0.001), while PAL was correlated more strongly with the non-locomotive NEAT score (r = 0.548, P < 0.001) than the locomotive NEAT score (r = 0.278, P = 0.10). Regarding accelerometer-obtained data, this questionnaire mainly reflected steps/day and the duration of light locomotive and non-locomotive daily activities. The NEAT score is a possible option for evaluating PAL in daily clinical practice. The present results indicated that non-locomotive activity may have a greater impact on PAL than locomotive activity in COPD patients.
AB - Physical inactivity is associated with comorbidities and mortality in chronic obstructive pulmonary disease (COPD) patients. Although non-exercise activity thermogenesis (NEAT) is important for evaluating the physical activity level (PAL) of patients with chronic diseases, it has not yet been assessed in COPD patients. This study included male patients with COPD (n = 28) and high risk for COPD (n = 8). Total energy expenditure (TEE) and basal metabolic rate (BMR) were measured using the doubly labeled water (DLW) method and indirect calorimetry, respectively. PAL was calculated as TEE/BMR, while the NEAT was obtained from a questionnaire. Physical activity was also assessed using an accelerometer. The total NEAT score was correlated with PAL (r = 0.534, P < 0.001), while PAL was correlated more strongly with the non-locomotive NEAT score (r = 0.548, P < 0.001) than the locomotive NEAT score (r = 0.278, P = 0.10). Regarding accelerometer-obtained data, this questionnaire mainly reflected steps/day and the duration of light locomotive and non-locomotive daily activities. The NEAT score is a possible option for evaluating PAL in daily clinical practice. The present results indicated that non-locomotive activity may have a greater impact on PAL than locomotive activity in COPD patients.
KW - Chronic obstructive pulmonary disease
KW - doubly labeled water method
KW - non-exercise activity thermogenesis
KW - physical activity level
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U2 - 10.1177/00368504221117064
DO - 10.1177/00368504221117064
M3 - Article
C2 - 36082951
AN - SCOPUS:85137600134
SN - 0036-8504
VL - 105
JO - Science Progress
JF - Science Progress
IS - 3
ER -