@article{8d1cf923207b48abb17937098cfcf4fe,
title = "In Situ Generation of Ruthenium Carbonyl Phosphine Complexes as a Versatile Method for the Development of Enantioselective C−O Bond Arylation",
abstract = "We report here a method for in situ generation of various ruthenium carbonyl phosphine catalysts for arylation via cleavage of inert aromatic carbon–oxygen bonds. The use of catalyst systems consisting of [RuCl2(CO)(p-cymene)], CsF, styrene, and phosphines enabled facile screening of phosphine ligands. Asymmetric C–O arylation was also achieved for atropo-enantioselective biaryl synthesis using a chiral monodentate phosphine ligand.",
keywords = "asymmetric synthesis, cleavage reactions, homogeneous catalysis, ruthenium, synthetic methods",
author = "Hikaru Kondo and Takuya Kochi and Fumitoshi Kakiuchi",
note = "Funding Information: F.K. thanks to financial support, in part, by the Promotion of Science (JSPS) KAKENHI Grant Number JP15H05839 in Middle Molecular Strategy, Japan. H.K. is grateful to JSPS for a Research Fellowship for Young Scientists (JP16J02904). T.K. is also grateful for financial support provided by JSPS KAKENHI Grant Number JP18H04271 in Precisely Designed Catalysts with Customized Scaffolding. We thank I. Suzuki at Keio University for experimental assistance. We are grateful to Prof. Y. Fujimoto (Keio University) for her assistance with correcting the specific rotations. Funding Information: F.K. thanks to financial support, in part, by the Promotion of Science (JSPS) KAKENHI Grant Number JP15H05839 in Middle Molecular Strategy, Japan. H.K. is grateful to JSPS for a Research Fellowship for Young Scientists (JP16J02904). T.K. is also grateful for financial support provided by JSPS KAKENHI Grant Number JP18H04271 in Precisely Designed Catalysts with Customized Scaffolding. We thank I. Suzuki at Keio University for experimental assistance. We are grateful to Prof. Y. Fujimoto (Keio University) for her assistance with correcting the specific rotations. Publisher Copyright: {\textcopyright} 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim",
year = "2020",
month = feb,
day = "6",
doi = "10.1002/chem.201905157",
language = "English",
volume = "26",
pages = "1737--1741",
journal = "Chemistry - A European Journal",
issn = "0947-6539",
publisher = "Wiley-VCH Verlag",
number = "8",
}