TY - JOUR
T1 - In vitro translation-based computations
AU - Sakakibara, Yasubumi
AU - Hohsaka, Takahiro
PY - 2004
Y1 - 2004
N2 - The translation system in a cell is a powerful molecular machine conducted by ribosomes, tRNAs, and several translation factors to synthesize proteins. The translation process is very accurate according to the genetic code and directed from 5′-end to 3′-end on messenger RNA. We employ the translation mechanism combined with four-base codon techniques to develop a molecular machine which computes finite automata (finite-state machine). We report some experimental results where we have succeeded to implement a finite automaton on an E. coli in vitro translation system with four-base codons.
AB - The translation system in a cell is a powerful molecular machine conducted by ribosomes, tRNAs, and several translation factors to synthesize proteins. The translation process is very accurate according to the genetic code and directed from 5′-end to 3′-end on messenger RNA. We employ the translation mechanism combined with four-base codon techniques to develop a molecular machine which computes finite automata (finite-state machine). We report some experimental results where we have succeeded to implement a finite automaton on an E. coli in vitro translation system with four-base codons.
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U2 - 10.1007/978-3-540-24628-2_19
DO - 10.1007/978-3-540-24628-2_19
M3 - Article
AN - SCOPUS:35048825335
SN - 0302-9743
VL - 2943
SP - 197
EP - 202
JO - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
JF - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
ER -