Inflammatory plaque with peripheral nodules: A new specific finding of cutaneous polyarteritis nodosa

Po Tak Chan, Akira Ishiko, Naoko Wada, Nao Yamamoto, Masayuki Amagai

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Cutaneous polyarteritis nodosa commonly affects the distal lower limbs, presenting as nodules, ulcers, and livedo reticularis. We report five cases to illustrate a new specific presentation of cutaneous polyarteritis nodosa on the trunk or proximal extremities. In the acute stage, lesions were tender erythematous plaques. On palpation, 1- to 2-cm diameter subcutaneous nodules were found along the periphery. The lesions responded to dapsone, aspirin, nonsteroidal antiinflammatory drugs, or systemic steroids and healed with postinflammatory hyperpigmentation. Systemic polyarteritis nodosa did not develop in any patient after a follow-up time ranging from 9 months to 9 years. The presence of small nodules at the periphery of an inflammatory plaque was a useful clinical clue, because this prompted us to suspect cutaneous polyarteritis nodosa when we encountered similar cases later, which could be confirmed histologically. In conclusion, cutaneous polyarteritis nodosa can present as inflammatory plaques on the trunk and proximal extremities, and the presence of peripheral nodules around these plaques constitutes a useful clinical clue to its diagnosis.

Original languageEnglish
Pages (from-to)320-325
Number of pages6
JournalJournal of the American Academy of Dermatology
Issue number2
Publication statusPublished - 2009 Feb

ASJC Scopus subject areas

  • Dermatology


Dive into the research topics of 'Inflammatory plaque with peripheral nodules: A new specific finding of cutaneous polyarteritis nodosa'. Together they form a unique fingerprint.

Cite this