Inhibitors of prostaglandin biosynthesis from ginger

Fumiyuki Kiuchi; Masaaki Shibuya; Ushio Sankawa

doi:10.1248/cpb.30.754

Inhibitors of prostaglandin biosynthesis from ginger

Fumiyuki Kiuchi, Masaaki Shibuya, Ushio Sankawa

Research output: Contribution to journal › Article › peer-review

158 Citations (Scopus)

Abstract

In addition to [6]-gingerol four new constituents were isolated as potent inhibitors of prostaglandin (PG) biosynthesis from ginger, the roots of Zingiber officinale Roscoe. Their structures were identified as [6]- and [10]-dehydrogingerdione (I and II) and [6]- and [10]-gingerdione (III and IV) by the interpretation of spectral data.

Original language	English
Pages (from-to)	754-757
Number of pages	4
Journal	Chemical and Pharmaceutical Bulletin
Volume	30
Issue number	2
DOIs	https://doi.org/10.1248/cpb.30.754
Publication status	Published - 1982
Externally published	Yes

Keywords

Zingiber officinale
Zingiberaceae
biosynthesis
dehydrogingerdione
ginger
gingerdione
gingerol
inhibitor
prostaglandin

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

Access to Document

10.1248/cpb.30.754

Cite this

@article{a46a3355af1b4127a9a7f0adc83635e7,

title = "Inhibitors of prostaglandin biosynthesis from ginger",

abstract = "In addition to [6]-gingerol four new constituents were isolated as potent inhibitors of prostaglandin (PG) biosynthesis from ginger, the roots of Zingiber officinale Roscoe. Their structures were identified as [6]- and [10]-dehydrogingerdione (I and II) and [6]- and [10]-gingerdione (III and IV) by the interpretation of spectral data.",

keywords = "Zingiber officinale, Zingiberaceae, biosynthesis, dehydrogingerdione, ginger, gingerdione, gingerol, inhibitor, prostaglandin",

author = "Fumiyuki Kiuchi and Masaaki Shibuya and Ushio Sankawa",

year = "1982",

doi = "10.1248/cpb.30.754",

language = "English",

volume = "30",

pages = "754--757",

journal = "Chemical and Pharmaceutical Bulletin",

issn = "0009-2363",

publisher = "Pharmaceutical Society of Japan",

number = "2",

}

TY - JOUR

T1 - Inhibitors of prostaglandin biosynthesis from ginger

AU - Kiuchi, Fumiyuki

AU - Shibuya, Masaaki

AU - Sankawa, Ushio

PY - 1982

Y1 - 1982

N2 - In addition to [6]-gingerol four new constituents were isolated as potent inhibitors of prostaglandin (PG) biosynthesis from ginger, the roots of Zingiber officinale Roscoe. Their structures were identified as [6]- and [10]-dehydrogingerdione (I and II) and [6]- and [10]-gingerdione (III and IV) by the interpretation of spectral data.

AB - In addition to [6]-gingerol four new constituents were isolated as potent inhibitors of prostaglandin (PG) biosynthesis from ginger, the roots of Zingiber officinale Roscoe. Their structures were identified as [6]- and [10]-dehydrogingerdione (I and II) and [6]- and [10]-gingerdione (III and IV) by the interpretation of spectral data.

KW - Zingiber officinale

KW - Zingiberaceae

KW - biosynthesis

KW - dehydrogingerdione

KW - ginger

KW - gingerdione

KW - gingerol

KW - inhibitor

KW - prostaglandin

UR - http://www.scopus.com/inward/record.url?scp=0019949095&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019949095&partnerID=8YFLogxK

U2 - 10.1248/cpb.30.754

DO - 10.1248/cpb.30.754

M3 - Article

C2 - 7094159

AN - SCOPUS:0019949095

SN - 0009-2363

VL - 30

SP - 754

EP - 757

JO - Chemical and Pharmaceutical Bulletin

JF - Chemical and Pharmaceutical Bulletin

IS - 2

ER -

Inhibitors of prostaglandin biosynthesis from ginger

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this