Abstract
The inhibitory effects of various synthetic oligosaccharides (1-8) on anti-lipid IV antiserum binding activity were examined by ELISA (enzyme linked immunosorbent assay). Compound 8, containing an epitope GlcA-4Meβ1-4Fuc of lipid IV, inhibited but precursers (1-5) of lipid IV did not inhibit the binding activity. In addition to the nonreducing end disaccharide derivative (6) having a methyl group at position 4 of glucuronic acid, its analogous compound (7) having no methyl groups was synthesized and their inhibition activities were compared. Moreover, the inhibitory effects of compounds (1-5) were examined using each antiserum.
| Original language | English |
|---|---|
| Pages (from-to) | 333-341 |
| Number of pages | 9 |
| Journal | Yakugaku Zasshi |
| Volume | 114 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 1994 Jan 1 |
Keywords
- Hyriopsis schlegelii
- anti-lipid IV antiserum
- inhibitory effect
- lipid IV
- synthetic octasaccharide
ASJC Scopus subject areas
- Pharmacology
- Pharmaceutical Science