Integrated Collection of Stem Cell Bank Data, a Data Portal for Standardized Stem Cell Information

Ying Chen, Kunie Sakurai, Sumihiro Maeda, Tohru Masui, Hideyuki Okano, Johannes Dewender, Stefanie Seltmann, Andreas Kurtz, Hiroshi Masuya, Yukio Nakamura, Michael Sheldon, Juliane Schneider, Glyn N. Stacey, Yulia Panina, Wataru Fujibuchi

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

The past decade has witnessed an extremely rapid increase in the number of newly established stem cell lines. However, due to the lack of a standardized format, data exchange among stem cell line resources has been challenging, and no system can search all stem cell lines across resources worldwide. To solve this problem, we have developed the Integrated Collection of Stem Cell Bank data (ICSCB) (http://icscb.stemcellinformatics.org/), the largest database search portal for stem cell line information, based on the standardized data items and terms of the MIACARM framework. Currently, ICSCB can retrieve >16,000 cell lines from four major data resources in Europe, Japan, and the United States. ICSCB is automatically updated to provide the latest cell line information, and its integrative search helps users collect cell line information for over 1,000 diseases, including many rare diseases worldwide, which has been a formidable task, thereby distinguishing itself from other database search portals.

Original languageEnglish
Pages (from-to)997-1005
Number of pages9
JournalStem cell reports
Volume16
Issue number4
DOIs
Publication statusPublished - 2021 Apr 13

Keywords

  • ICSCB
  • MIACARM
  • cell line statistics
  • data integration
  • data portal
  • disease classification
  • diseased iPS cell line
  • international stem cell bank initiative
  • standardized search
  • stem cell line information

ASJC Scopus subject areas

  • Biochemistry
  • Genetics
  • Developmental Biology
  • Cell Biology

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