Interfacial characterization of thermoresponsive surfaces grafted with high-density polymer chains

Aya Mizutani, Akihiko Kikuchi, Jun Kobayashi, Yoshikatsu Akiyama, Hideko Kanazawa, Teruo Okano

Research output: Contribution to conferencePaperpeer-review


In the present research, thermoresponsive polymer brush surfaces grafted with high-density poly(N-isopropylacrylamide) (PIPAAm) are prepared by surface-initiated atom transfer radical polymerization (ATRP) using poly(p-chloromethylstyrene) as an ATRP initiator. Thermoresponsive surface characteristics are analyzed for the surfaces prepared at different reaction times. We succeeded to adhere endodermis cells (ECs) onto PIPAAm brush surfaces at 37°C while these cells detached by incubation at 20°C. Grafted polymer architecture as well as the grafted amount of PIPAAm chains should have important influence on cell adhesion/detachment behavior.

Original languageEnglish
Number of pages1
Publication statusPublished - 2006 Oct 19
Event55th SPSJ Annual Meeting - Nagoya, Japan
Duration: 2006 May 242006 May 26


Other55th SPSJ Annual Meeting


  • Cell adhesion
  • High-density polymer grafted surfaces
  • Poly(N-isopropylacrylamide)
  • Surface-initiated atom transfer radical polymerization
  • Thermoresponsive polymer

ASJC Scopus subject areas

  • Engineering(all)


Dive into the research topics of 'Interfacial characterization of thermoresponsive surfaces grafted with high-density polymer chains'. Together they form a unique fingerprint.

Cite this