Intracardiac echocardiography for percutaneous closure of atrial septal defects: Initial experiences in Japan

Sayaka Shimizu, Akio Kawamura, Takahide Arai, Yohei Ohno, Satoshi Mogi, Masaki Kodaira, Atsushi Anzai, Takashi Kawakami, Hideaki Kanazawa, Kentaro Hayashida, Shinsuke Yuasa, Yuichiro Maekawa, Keiichi Fukuda

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)


Transcatheter closure of secundum atrial septal defect (ASD) has been widely performed as a less invasive alternative to surgery with zero mortality so far in Japan. In the US and Europe, intracardiac echocardiography (ICE) has replaced transesophageal echocardiography (TEE) as a primary imaging tool during percutaneous ASD closure. However, the experience of ICE in ASD closure is limited in Japan. Consecutive 51 patients underwent percutaneous ASD closure with ICE guidance. Clinical results were compared to those of 41 patients who underwent ASD closure with TEE guidance. Pediatric patients and patients with multiple ASDs who were expected to need multiple devices were excluded. Success rate was similar in both groups (ICE 96.1 %, TEE 92.7 %). Catheterization laboratory time was significantly shortened with ICE than with TEE (131 vs. 155 min, p = 0.0003). There were no complications related to the use of ICE. ICE-guided ASD closure is feasible in most adult patients. ICE is superior to TEE in shortening catheterization laboratory time and eliminating general anesthesia, and can potentially replace TEE as the primary image guide during percutaneous ASD closure.

Original languageEnglish
Pages (from-to)368-373
Number of pages6
JournalCardiovascular Intervention and Therapeutics
Issue number4
Publication statusPublished - 2013 Oct


  • ASD closure
  • Amplatzer
  • ICE

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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