Intraocular pressure elevation after Descemet's stripping endothelial keratoplasty

Naoki Ozeki, Kenya Yuki, Daisuke Shiba, Shigeto Shimmura, Dogru Murat, Kazuo Tsubota

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)


Purpose: To investigate the incidence of intraocular pressure (IOP) elevation after Descemet's stripping endothelial keratoplasty (DSEK) and associated clinical findings. Methods: Forty-eight eyes of 46 patients who underwent DSEK were studied in this single-center retrospective study. IOP elevation was defined as the presence of an increase in IOP above 21 mmHg lasting at least two - months, the need to introduce topical/oral antiglaucoma medications for at least two months, and the need for surgical therapy for uncontrolled IOP. Patients with pre-existing glaucoma or patients who were using antiglaucoma drugs before DSEK were excluded according to the protocol of the study. The incidence of post-DSEK IOP elevation was investigated. Results: The incidence of IOP elevation after DSEK was 16.7%. Glaucoma therapy following DSEK was needed in eight eyes of eight patients. IOP elevations were diagnosed from two to ten months after DSEK. There was no statistical difference in the survival probabilities of patients with different preoperative diagnoses. Pre-op IOP was observed to be a risk factor of IOP elevation in this series. Conclusions: IOP elevation appears to be a common postoperative complication of DSEK. Patients without preexisting glaucoma but with higher pre-op IOP need to be followed up carefully after DSEK.

Original languageEnglish
Pages (from-to)307-311
Number of pages5
JournalJapanese Journal of Ophthalmology
Issue number4
Publication statusPublished - 2012 Jul


  • Descemet's stripping endothelial keratoplasty
  • Glaucoma
  • Intraocular pressure

ASJC Scopus subject areas

  • Ophthalmology


Dive into the research topics of 'Intraocular pressure elevation after Descemet's stripping endothelial keratoplasty'. Together they form a unique fingerprint.

Cite this