Intraoperative lymphatic mapping and sentinel lymph node sampling in esophageal and gastric cancer

Yuko Kitagawa, Hirofumi Fujii, Makio Mukai, Tetsuro Kubota, Nobutoshi Ando, Soji Ozawa, Yoshihide Ohtani, Toshiharu Furukawa, Masashi Yoshida, Eiichi Nakamura, Jun Ichi Matsuda, Yoshimasa Shimizu, Kayoko Nakamura, Koichiro Kumai, Atsushi Kubo, Masaki Kitajima

Research output: Contribution to journalReview articlepeer-review

54 Citations (Scopus)


Recent studies for SN mapping of esophageal and gastric carcinoma show that the SN concept is valid even for upper GI cancers with multidirectional and complicated lymphatic flow. The relatively high incidence of anatomic skip metastasis can be attributed to aberrant distribution of SNs. An individualized and minimally invasive surgical approach can be applicable to management of esophageal and gastric carcinoma based on SN status. Although there are several issues to be resolved, this novel procedure has the potential for great benefit to improve quality control in the treatment of upper GI cancer. Well-designed clinical trials of lymphatic mapping for upper GI cancer will be essential to determine whether this technique is widely applicable in the management of these tumors.

Original languageEnglish
Pages (from-to)293-304
Number of pages12
JournalSurgical Oncology Clinics of North America
Issue number2
Publication statusPublished - 2002 Apr

ASJC Scopus subject areas

  • Surgery
  • Oncology


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