Intravascular pancuronium bromide infusion for prenatal diagnosis of twin-twin transfusion syndrome

Mamoru Tanaka; Michiya Natori; Hitoshi Ishimoto; Hachiro Kohno; Toshifumi Kobayashi; Shiro Nozawa

doi:10.1159/000263648

Intravascular pancuronium bromide infusion for prenatal diagnosis of twin-twin transfusion syndrome

Mamoru Tanaka, Michiya Natori, Hitoshi Ishimoto, Hachiro Kohno, Toshifumi Kobayashi, Shiro Nozawa

Department of Obstetrics and Gynecology (Obstetrics)

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

The diagnosis ot twin-twin transfusion syndrome remains a problem. Intravascular infusion of pancuronium bromide, a nondepolarizing neuromuscular blocking agent, for the smaller of a set of twins demonstrated paralysis of both twins in one case. However, in a second case, paralysis was shown only in the smaller twin who demonstrated no transplacental vascular communications postnatally. We suggest that infusion of pancuronium bromide, ‘pancuronium test’, is a simple and safe method for confirming transplacental communications and aids in the diagnosis of twin-twin transfusion syndrome.

Original language	English
Pages (from-to)	36-40
Number of pages	5
Journal	Fetal Diagnosis and Therapy
Volume	7
Issue number	1
DOIs	https://doi.org/10.1159/000263648
Publication status	Published - 1992 Jan 1

Keywords

Fetal heart rate tracing
Intravascular infusion
Pancuronium bromide
Prenatal diagnosis
Syndrome
Twin-twin transfusion

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Embryology
Radiology Nuclear Medicine and imaging
Obstetrics and Gynaecology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1159/000263648

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abstract = "The diagnosis ot twin-twin transfusion syndrome remains a problem. Intravascular infusion of pancuronium bromide, a nondepolarizing neuromuscular blocking agent, for the smaller of a set of twins demonstrated paralysis of both twins in one case. However, in a second case, paralysis was shown only in the smaller twin who demonstrated no transplacental vascular communications postnatally. We suggest that infusion of pancuronium bromide, {\textquoteleft}pancuronium test{\textquoteright}, is a simple and safe method for confirming transplacental communications and aids in the diagnosis of twin-twin transfusion syndrome.",

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AU - Tanaka, Mamoru

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AU - Ishimoto, Hitoshi

AU - Kohno, Hachiro

AU - Kobayashi, Toshifumi

AU - Nozawa, Shiro

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N2 - The diagnosis ot twin-twin transfusion syndrome remains a problem. Intravascular infusion of pancuronium bromide, a nondepolarizing neuromuscular blocking agent, for the smaller of a set of twins demonstrated paralysis of both twins in one case. However, in a second case, paralysis was shown only in the smaller twin who demonstrated no transplacental vascular communications postnatally. We suggest that infusion of pancuronium bromide, ‘pancuronium test’, is a simple and safe method for confirming transplacental communications and aids in the diagnosis of twin-twin transfusion syndrome.

AB - The diagnosis ot twin-twin transfusion syndrome remains a problem. Intravascular infusion of pancuronium bromide, a nondepolarizing neuromuscular blocking agent, for the smaller of a set of twins demonstrated paralysis of both twins in one case. However, in a second case, paralysis was shown only in the smaller twin who demonstrated no transplacental vascular communications postnatally. We suggest that infusion of pancuronium bromide, ‘pancuronium test’, is a simple and safe method for confirming transplacental communications and aids in the diagnosis of twin-twin transfusion syndrome.

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KW - Intravascular infusion

KW - Pancuronium bromide

KW - Prenatal diagnosis

KW - Syndrome

KW - Twin-twin transfusion

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Intravascular pancuronium bromide infusion for prenatal diagnosis of twin-twin transfusion syndrome

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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