(+)-Isoamericanol A: A Plant Growth Inhibitor from Heliotropium indicum

Sirinapa Chaipon, Sutjaritpan Boonmee, Arihiro Iwasaki, Kiyotake Suenaga, Hisashi Kato-Noguchi

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


A plant growth inhibitory substance was isolated from Heliotropium indicum by bioassay-guided purification and characterized to be (+)-isoamericanol A. (+)-Isoamericanol A significantly inhibited seedling growth of cress at a concentration greater than 0.1 mM. The concentrations of (+)-isoamericanol A required for 50% growth inhibition of cress roots and hypocotyls were 0.5 and 0.4 mM, respectively. This inhibition indicates that (+)-isoamericanol A had a growth inhibitory activity and may contribute to the allelopathic effect of H. indicum. This report is the first on the plant growth inhibitory activity of (+)-isoamericanol A as an allelopathic substance.

Original languageEnglish
JournalNatural product communications
Issue number5
Publication statusPublished - 2019 May


  • Allelopathic activity
  • Growth inhibition
  • Heliotropium indicum
  • Natural product

ASJC Scopus subject areas

  • Pharmacology
  • Plant Science
  • Drug Discovery
  • Complementary and alternative medicine


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