Isolated recurrence of prostate cancer to the anterior urethra 5 years after radiation therapy

Shinnosuke Fujiwara; Masaru Ishida; Eri Arai; Yuto Baba; Tadatsugu Anno; Hiroaki Kobayashi; Yasumasa Miyazaki

doi:10.1002/iju5.12394

Isolated recurrence of prostate cancer to the anterior urethra 5 years after radiation therapy

Shinnosuke Fujiwara, Masaru Ishida, Eri Arai, Yuto Baba, Tadatsugu Anno, Hiroaki Kobayashi, Yasumasa Miyazaki

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Introduction: Primary or metastatic urethral tumors are extremely rare. However, treatment strategies differ between primary and metastatic tumors. Therefore, establishing an accurate diagnosis is critically needed for initiating timely and appropriate therapy. Case presentation: We describe the case of a 79-year-old man with prostate cancer treated with radiotherapy and androgen deprivation therapy. He presented with macroscopic hematuria as a symptom of anterior urethral tumor at follow-up. Endoscopic tumor resection was performed. Hematoxylin and eosin staining showed adenocarcinoma component. Immunohistochemical staining revealed presence of metastatic prostate cancer to the urethra. Conclusion: Regarding urethral tumors diagnosis, urologists should consider the possibility of metastasis from prostate cancer and perform immunohistochemical examination for establishing accurate diagnosis. Furthermore, if androgen deprivation therapy fails to suppress symptoms, radiotherapy or urethrectomy might be considered.

Original language	English
Pages (from-to)	58-61
Number of pages	4
Journal	IJU Case Reports
Volume	5
Issue number	1
DOIs	https://doi.org/10.1002/iju5.12394
Publication status	Published - 2022 Jan

ASJC Scopus subject areas

Urology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1002/iju5.12394

Cite this

@article{78017651ef7049d3a2abb6991e0f9665,

title = "Isolated recurrence of prostate cancer to the anterior urethra 5 years after radiation therapy",

abstract = "Introduction: Primary or metastatic urethral tumors are extremely rare. However, treatment strategies differ between primary and metastatic tumors. Therefore, establishing an accurate diagnosis is critically needed for initiating timely and appropriate therapy. Case presentation: We describe the case of a 79-year-old man with prostate cancer treated with radiotherapy and androgen deprivation therapy. He presented with macroscopic hematuria as a symptom of anterior urethral tumor at follow-up. Endoscopic tumor resection was performed. Hematoxylin and eosin staining showed adenocarcinoma component. Immunohistochemical staining revealed presence of metastatic prostate cancer to the urethra. Conclusion: Regarding urethral tumors diagnosis, urologists should consider the possibility of metastasis from prostate cancer and perform immunohistochemical examination for establishing accurate diagnosis. Furthermore, if androgen deprivation therapy fails to suppress symptoms, radiotherapy or urethrectomy might be considered.",

author = "Shinnosuke Fujiwara and Masaru Ishida and Eri Arai and Yuto Baba and Tadatsugu Anno and Hiroaki Kobayashi and Yasumasa Miyazaki",

note = "Funding Information: This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Publisher Copyright: {\textcopyright} 2021 The Authors. IJU Case Reports published by John Wiley & Sons Australia, Ltd on behalf of Japanese Urological Association",

year = "2022",

month = jan,

doi = "10.1002/iju5.12394",

language = "English",

volume = "5",

pages = "58--61",

journal = "IJU Case Reports",

issn = "2577-171X",

publisher = "John Wiley and Sons Inc.",

number = "1",

}

TY - JOUR

T1 - Isolated recurrence of prostate cancer to the anterior urethra 5 years after radiation therapy

AU - Fujiwara, Shinnosuke

AU - Ishida, Masaru

AU - Arai, Eri

AU - Baba, Yuto

AU - Anno, Tadatsugu

AU - Kobayashi, Hiroaki

AU - Miyazaki, Yasumasa

N1 - Funding Information: This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Publisher Copyright: © 2021 The Authors. IJU Case Reports published by John Wiley & Sons Australia, Ltd on behalf of Japanese Urological Association

PY - 2022/1

Y1 - 2022/1

N2 - Introduction: Primary or metastatic urethral tumors are extremely rare. However, treatment strategies differ between primary and metastatic tumors. Therefore, establishing an accurate diagnosis is critically needed for initiating timely and appropriate therapy. Case presentation: We describe the case of a 79-year-old man with prostate cancer treated with radiotherapy and androgen deprivation therapy. He presented with macroscopic hematuria as a symptom of anterior urethral tumor at follow-up. Endoscopic tumor resection was performed. Hematoxylin and eosin staining showed adenocarcinoma component. Immunohistochemical staining revealed presence of metastatic prostate cancer to the urethra. Conclusion: Regarding urethral tumors diagnosis, urologists should consider the possibility of metastasis from prostate cancer and perform immunohistochemical examination for establishing accurate diagnosis. Furthermore, if androgen deprivation therapy fails to suppress symptoms, radiotherapy or urethrectomy might be considered.

AB - Introduction: Primary or metastatic urethral tumors are extremely rare. However, treatment strategies differ between primary and metastatic tumors. Therefore, establishing an accurate diagnosis is critically needed for initiating timely and appropriate therapy. Case presentation: We describe the case of a 79-year-old man with prostate cancer treated with radiotherapy and androgen deprivation therapy. He presented with macroscopic hematuria as a symptom of anterior urethral tumor at follow-up. Endoscopic tumor resection was performed. Hematoxylin and eosin staining showed adenocarcinoma component. Immunohistochemical staining revealed presence of metastatic prostate cancer to the urethra. Conclusion: Regarding urethral tumors diagnosis, urologists should consider the possibility of metastasis from prostate cancer and perform immunohistochemical examination for establishing accurate diagnosis. Furthermore, if androgen deprivation therapy fails to suppress symptoms, radiotherapy or urethrectomy might be considered.

UR - http://www.scopus.com/inward/record.url?scp=85118370505&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85118370505&partnerID=8YFLogxK

U2 - 10.1002/iju5.12394

DO - 10.1002/iju5.12394

M3 - Article

AN - SCOPUS:85118370505

SN - 2577-171X

VL - 5

SP - 58

EP - 61

JO - IJU Case Reports

JF - IJU Case Reports

IS - 1

ER -

Isolated recurrence of prostate cancer to the anterior urethra 5 years after radiation therapy

Abstract

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this