Isolation and stereostructure of aurilide, a novel cyclodepsipeptide from the Japanese sea hare Dolabella auricularia

Kiyotake Suenaga; Tsuyoshi Mutou; Takunobu Shibata; Takashi Itoh; Hideo Kigoshi; Kiyoyuki Yamada

doi:10.1016/S0040-4039(96)01464-5

Isolation and stereostructure of aurilide, a novel cyclodepsipeptide from the Japanese sea hare Dolabella auricularia

Kiyotake Suenaga, Tsuyoshi Mutou, Takunobu Shibata, Takashi Itoh, Hideo Kigoshi, Kiyoyuki Yamada

Research output: Contribution to journal › Article › peer-review

60 Citations (Scopus)

Abstract

Aurilide (1), a new 26-membered cyclodepsipeptide, has been isolated from the Japanese sea hare Dolabella auricularia. The gross structure of 1 was established by spectroscopic analysis. The absolute stereostructure of 1 was determined by HPLC analysis of amino acid components and isoleucic acid obtained from acidic hydrolysis of 1 and by the enantioselective synthesis of the tris(p-bromobenzoate) 3 derived from the dihydroxy acid moiety.

Original language	English
Pages (from-to)	6771-6774
Number of pages	4
Journal	Tetrahedron Letters
Volume	37
Issue number	37
DOIs	https://doi.org/10.1016/S0040-4039(96)01464-5
Publication status	Published - 1996 Sept 9
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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title = "Isolation and stereostructure of aurilide, a novel cyclodepsipeptide from the Japanese sea hare Dolabella auricularia",

abstract = "Aurilide (1), a new 26-membered cyclodepsipeptide, has been isolated from the Japanese sea hare Dolabella auricularia. The gross structure of 1 was established by spectroscopic analysis. The absolute stereostructure of 1 was determined by HPLC analysis of amino acid components and isoleucic acid obtained from acidic hydrolysis of 1 and by the enantioselective synthesis of the tris(p-bromobenzoate) 3 derived from the dihydroxy acid moiety.",

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T1 - Isolation and stereostructure of aurilide, a novel cyclodepsipeptide from the Japanese sea hare Dolabella auricularia

AU - Suenaga, Kiyotake

AU - Mutou, Tsuyoshi

AU - Shibata, Takunobu

AU - Itoh, Takashi

AU - Kigoshi, Hideo

AU - Yamada, Kiyoyuki

PY - 1996/9/9

Y1 - 1996/9/9

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AB - Aurilide (1), a new 26-membered cyclodepsipeptide, has been isolated from the Japanese sea hare Dolabella auricularia. The gross structure of 1 was established by spectroscopic analysis. The absolute stereostructure of 1 was determined by HPLC analysis of amino acid components and isoleucic acid obtained from acidic hydrolysis of 1 and by the enantioselective synthesis of the tris(p-bromobenzoate) 3 derived from the dihydroxy acid moiety.

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JF - Tetrahedron Letters

IS - 37

ER -

Isolation and stereostructure of aurilide, a novel cyclodepsipeptide from the Japanese sea hare Dolabella auricularia

Abstract

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