Isolation of inohanalactone, a γ-butyrolactone, from Nocardia Inohanensis IFM0092T

Natsumi Kobayashi; Yasumasa Hara; Midori A. Arai; Shoko Hara; Tohru Gonoi; Takashi Yaguchi; Masami Ishibashi

doi:10.3987/COM-19-S(F)11

Isolation of inohanalactone, a γ-butyrolactone, from Nocardia Inohanensis IFM0092^T

Natsumi Kobayashi, Yasumasa Hara, Midori A. Arai, Shoko Hara, Tohru Gonoi, Takashi Yaguchi, Masami Ishibashi

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Because research on the genus Nocardia has not progressed as compared to the extensively studied genus Streptomyces, Nocardia is considered as a useful undeveloped resource for exploring natural products. In this study, a new γ-butyrolactone derivative, named inohanalactone (1), was isolated from Nocardia inohanensis IFM0092^T. Inohanalactone possesses an aliphatic side chain containing 8 carbons, a vicinal diol, and a cis double bond. Inohanalactone was produced by N. inohanensis IFM0092^T in the modified Czapek-Dox medium, whereas it was not produced in other media such as Nutrient broth, Waksman, and Yeast-Malt-Glucose media.

Original language	English
Pages (from-to)	312-317
Number of pages	6
Journal	Heterocycles
Volume	101
Issue number	1
DOIs	https://doi.org/10.3987/COM-19-S(F)11
Publication status	Published - 2020
Externally published	Yes

ASJC Scopus subject areas

Analytical Chemistry
Pharmacology
Organic Chemistry

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title = "Isolation of inohanalactone, a γ-butyrolactone, from Nocardia Inohanensis IFM0092T ",

abstract = "Because research on the genus Nocardia has not progressed as compared to the extensively studied genus Streptomyces, Nocardia is considered as a useful undeveloped resource for exploring natural products. In this study, a new γ-butyrolactone derivative, named inohanalactone (1), was isolated from Nocardia inohanensis IFM0092T. Inohanalactone possesses an aliphatic side chain containing 8 carbons, a vicinal diol, and a cis double bond. Inohanalactone was produced by N. inohanensis IFM0092T in the modified Czapek-Dox medium, whereas it was not produced in other media such as Nutrient broth, Waksman, and Yeast-Malt-Glucose media.",

author = "Natsumi Kobayashi and Yasumasa Hara and Arai, {Midori A.} and Shoko Hara and Tohru Gonoi and Takashi Yaguchi and Masami Ishibashi",

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doi = "10.3987/COM-19-S(F)11",

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T1 - Isolation of inohanalactone, a γ-butyrolactone, from Nocardia Inohanensis IFM0092T

AU - Kobayashi, Natsumi

AU - Hara, Yasumasa

AU - Arai, Midori A.

AU - Hara, Shoko

AU - Gonoi, Tohru

AU - Yaguchi, Takashi

AU - Ishibashi, Masami

PY - 2020

Y1 - 2020

N2 - Because research on the genus Nocardia has not progressed as compared to the extensively studied genus Streptomyces, Nocardia is considered as a useful undeveloped resource for exploring natural products. In this study, a new γ-butyrolactone derivative, named inohanalactone (1), was isolated from Nocardia inohanensis IFM0092T. Inohanalactone possesses an aliphatic side chain containing 8 carbons, a vicinal diol, and a cis double bond. Inohanalactone was produced by N. inohanensis IFM0092T in the modified Czapek-Dox medium, whereas it was not produced in other media such as Nutrient broth, Waksman, and Yeast-Malt-Glucose media.

AB - Because research on the genus Nocardia has not progressed as compared to the extensively studied genus Streptomyces, Nocardia is considered as a useful undeveloped resource for exploring natural products. In this study, a new γ-butyrolactone derivative, named inohanalactone (1), was isolated from Nocardia inohanensis IFM0092T. Inohanalactone possesses an aliphatic side chain containing 8 carbons, a vicinal diol, and a cis double bond. Inohanalactone was produced by N. inohanensis IFM0092T in the modified Czapek-Dox medium, whereas it was not produced in other media such as Nutrient broth, Waksman, and Yeast-Malt-Glucose media.

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Isolation of inohanalactone, a γ-butyrolactone, from Nocardia Inohanensis IFM0092^T

Abstract

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