Keio Uterus Transplantation Research: From Basic Research toward Future Clinical Application

Iori Kisu, Kouji Banno, Yusuke Matoba, Yohei Yamada, Katsura Emoto, Yohei Masugi, Kentaro Matsubara, Hideaki Obara, Daisuke Aoki

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


Uterus transplantation (UTx) is now a potential option to allow women with uterine factor infertility to give birth. However, UTx is still at an experimental stage, and basic animal studies, including in nonhuman primates, are needed for the accumulation of data prior to clinical application. Considering that UTx may provide new hope to Japanese women, we launched UTx research in 2009 and have since accumulated a large archive of results in the UTx research field. Furthermore, we have carried out various activities aimed at the implementation of clinical applications of UTx in Japan while clarifying the ethical and social issues involved. Currently, the clinical application of UTx in Japan is just around the corner, and it is expected that UTx research will develop further in the future. Herein, we summarize our basic experiences using non-human primates and our activities with the goal of future clinical applications.

Original languageEnglish
Pages (from-to)33-43
Number of pages11
JournalKeio Journal of Medicine
Issue number2
Publication statusPublished - 2022


  • cynomolgus macaque
  • non-human primate
  • surrogacy
  • uterine factor infertility
  • uterus transplantation

ASJC Scopus subject areas

  • Medicine(all)


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