Knot-Tying Force During Suturing and Wound Healing in the Gastrointestinal Tract

Junya Oguma; Soji Ozawa; Yasuhide Morikawa; Toshiharu Furukawa; Yuko Kitagawa; Masakazu Ueda; Masaki Kitajima

doi:10.1016/j.jss.2006.12.008

Knot-Tying Force During Suturing and Wound Healing in the Gastrointestinal Tract

Junya Oguma, Soji Ozawa, Yasuhide Morikawa, Toshiharu Furukawa, Yuko Kitagawa, Masakazu Ueda, Masaki Kitajima

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Background: Objective data should be obtained to determine the most suitable knot-tying force for appropriate suturing during robotic surgery. The purpose of this study was to estimate the appropriate force by investigating the efficiency of wound healing in the gastrointestinal tract in dog models. Methods: We cut and sutured the stomach and jejunum of 12 beagles, using different magnitudes of knot-tying forces. The relationship between the knot-tying force and variations in the density of the microvessels and basic-fibroblast growth factor (bFGF)-positive cells were evaluated. Results: On the 7th postoperative day (POD) in the stomach, and the 7th and 11th POD in the jejunum, the density of the microvessels in the submucosa at the sites of cutting and ligation was higher for the knot-tying force of 1.5 N than for any other forces used. On the 4th and 7th POD in the stomach and 11th POD in the jejunum, the density of bFGF-positive cell in the mucosa was higher for the knot-tying force of 1.5 N than for any of the other forces used. Conclusions: By assessing the efficiency of wound healing, it was determined that the knot-tying force of 1.5 N may be the most appropriate for optimal wound healing in the gastrointestinal tract of the beagles.

Original language	English
Pages (from-to)	129-134
Number of pages	6
Journal	Journal of Surgical Research
Volume	140
Issue number	1
DOIs	https://doi.org/10.1016/j.jss.2006.12.008
Publication status	Published - 2007 Jun 1

Keywords

a sense of touch
knot-tying force
robotic surgery
wound healing

ASJC Scopus subject areas

Surgery

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10.1016/j.jss.2006.12.008

Cite this

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title = "Knot-Tying Force During Suturing and Wound Healing in the Gastrointestinal Tract",

abstract = "Background: Objective data should be obtained to determine the most suitable knot-tying force for appropriate suturing during robotic surgery. The purpose of this study was to estimate the appropriate force by investigating the efficiency of wound healing in the gastrointestinal tract in dog models. Methods: We cut and sutured the stomach and jejunum of 12 beagles, using different magnitudes of knot-tying forces. The relationship between the knot-tying force and variations in the density of the microvessels and basic-fibroblast growth factor (bFGF)-positive cells were evaluated. Results: On the 7th postoperative day (POD) in the stomach, and the 7th and 11th POD in the jejunum, the density of the microvessels in the submucosa at the sites of cutting and ligation was higher for the knot-tying force of 1.5 N than for any other forces used. On the 4th and 7th POD in the stomach and 11th POD in the jejunum, the density of bFGF-positive cell in the mucosa was higher for the knot-tying force of 1.5 N than for any of the other forces used. Conclusions: By assessing the efficiency of wound healing, it was determined that the knot-tying force of 1.5 N may be the most appropriate for optimal wound healing in the gastrointestinal tract of the beagles.",

keywords = "a sense of touch, knot-tying force, robotic surgery, wound healing",

author = "Junya Oguma and Soji Ozawa and Yasuhide Morikawa and Toshiharu Furukawa and Yuko Kitagawa and Masakazu Ueda and Masaki Kitajima",

note = "Funding Information: We acknowledge the financial assistance of the Research Fund of Mitsukoshi Health and Welfare Foundation 2003.",

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T1 - Knot-Tying Force During Suturing and Wound Healing in the Gastrointestinal Tract

AU - Oguma, Junya

AU - Ozawa, Soji

AU - Morikawa, Yasuhide

AU - Furukawa, Toshiharu

AU - Kitagawa, Yuko

AU - Ueda, Masakazu

AU - Kitajima, Masaki

N1 - Funding Information: We acknowledge the financial assistance of the Research Fund of Mitsukoshi Health and Welfare Foundation 2003.

PY - 2007/6/1

Y1 - 2007/6/1

N2 - Background: Objective data should be obtained to determine the most suitable knot-tying force for appropriate suturing during robotic surgery. The purpose of this study was to estimate the appropriate force by investigating the efficiency of wound healing in the gastrointestinal tract in dog models. Methods: We cut and sutured the stomach and jejunum of 12 beagles, using different magnitudes of knot-tying forces. The relationship between the knot-tying force and variations in the density of the microvessels and basic-fibroblast growth factor (bFGF)-positive cells were evaluated. Results: On the 7th postoperative day (POD) in the stomach, and the 7th and 11th POD in the jejunum, the density of the microvessels in the submucosa at the sites of cutting and ligation was higher for the knot-tying force of 1.5 N than for any other forces used. On the 4th and 7th POD in the stomach and 11th POD in the jejunum, the density of bFGF-positive cell in the mucosa was higher for the knot-tying force of 1.5 N than for any of the other forces used. Conclusions: By assessing the efficiency of wound healing, it was determined that the knot-tying force of 1.5 N may be the most appropriate for optimal wound healing in the gastrointestinal tract of the beagles.

AB - Background: Objective data should be obtained to determine the most suitable knot-tying force for appropriate suturing during robotic surgery. The purpose of this study was to estimate the appropriate force by investigating the efficiency of wound healing in the gastrointestinal tract in dog models. Methods: We cut and sutured the stomach and jejunum of 12 beagles, using different magnitudes of knot-tying forces. The relationship between the knot-tying force and variations in the density of the microvessels and basic-fibroblast growth factor (bFGF)-positive cells were evaluated. Results: On the 7th postoperative day (POD) in the stomach, and the 7th and 11th POD in the jejunum, the density of the microvessels in the submucosa at the sites of cutting and ligation was higher for the knot-tying force of 1.5 N than for any other forces used. On the 4th and 7th POD in the stomach and 11th POD in the jejunum, the density of bFGF-positive cell in the mucosa was higher for the knot-tying force of 1.5 N than for any of the other forces used. Conclusions: By assessing the efficiency of wound healing, it was determined that the knot-tying force of 1.5 N may be the most appropriate for optimal wound healing in the gastrointestinal tract of the beagles.

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Knot-Tying Force During Suturing and Wound Healing in the Gastrointestinal Tract

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Keywords

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