Kohamaic acids A and B, novel cytotoxic sesterterpenic acids, from the marine sponge Ircinia sp

Susumu Kokubo; Kentaro Yogi; Md Jasim Uddin; Toshiyasu Inuzuka; Kiyotake Suenaga; Katsuhiro Ueda; Daisuke Uemura

doi:10.1246/cl.2001.176

Kohamaic acids A and B, novel cytotoxic sesterterpenic acids, from the marine sponge Ircinia sp

Susumu Kokubo, Kentaro Yogi, Md Jasim Uddin, Toshiyasu Inuzuka, Kiyotake Suenaga, Katsuhiro Ueda, Daisuke Uemura

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

Two new sesterterpenic acids, which exhibited moderate cytotoxicity, were isolated from the marine sponge Ircinia sp. Their absolute stereochemistries were determined by spectroscopic and chemical analyses. Their configurations at C15 were different from those of previously isolated sesterterpenes. This result suggests the existence of a (14Z)-geranylfarnesyl pyrophosphate, which is yet unknown in nature.

Original language	English
Pages (from-to)	176-177
Number of pages	2
Journal	Chemistry Letters
Issue number	2
DOIs	https://doi.org/10.1246/cl.2001.176
Publication status	Published - 2001
Externally published	Yes

ASJC Scopus subject areas

Chemistry(all)

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1246/cl.2001.176

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title = "Kohamaic acids A and B, novel cytotoxic sesterterpenic acids, from the marine sponge Ircinia sp",

abstract = "Two new sesterterpenic acids, which exhibited moderate cytotoxicity, were isolated from the marine sponge Ircinia sp. Their absolute stereochemistries were determined by spectroscopic and chemical analyses. Their configurations at C15 were different from those of previously isolated sesterterpenes. This result suggests the existence of a (14Z)-geranylfarnesyl pyrophosphate, which is yet unknown in nature.",

author = "Susumu Kokubo and Kentaro Yogi and Uddin, {Md Jasim} and Toshiyasu Inuzuka and Kiyotake Suenaga and Katsuhiro Ueda and Daisuke Uemura",

year = "2001",

doi = "10.1246/cl.2001.176",

language = "English",

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journal = "Chemistry Letters",

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T1 - Kohamaic acids A and B, novel cytotoxic sesterterpenic acids, from the marine sponge Ircinia sp

AU - Kokubo, Susumu

AU - Yogi, Kentaro

AU - Uddin, Md Jasim

AU - Inuzuka, Toshiyasu

AU - Suenaga, Kiyotake

AU - Ueda, Katsuhiro

AU - Uemura, Daisuke

PY - 2001

Y1 - 2001

N2 - Two new sesterterpenic acids, which exhibited moderate cytotoxicity, were isolated from the marine sponge Ircinia sp. Their absolute stereochemistries were determined by spectroscopic and chemical analyses. Their configurations at C15 were different from those of previously isolated sesterterpenes. This result suggests the existence of a (14Z)-geranylfarnesyl pyrophosphate, which is yet unknown in nature.

AB - Two new sesterterpenic acids, which exhibited moderate cytotoxicity, were isolated from the marine sponge Ircinia sp. Their absolute stereochemistries were determined by spectroscopic and chemical analyses. Their configurations at C15 were different from those of previously isolated sesterterpenes. This result suggests the existence of a (14Z)-geranylfarnesyl pyrophosphate, which is yet unknown in nature.

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DO - 10.1246/cl.2001.176

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ER -

Kohamaic acids A and B, novel cytotoxic sesterterpenic acids, from the marine sponge Ircinia sp

Abstract

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