TY - JOUR
T1 - Laparoscopic vaginoplasty procedure using a modified peritoneal pull-down technique with uterine strand incision in patients with mayer–rokitansky–küster–hauser syndrome
T2 - Kisu modification
AU - Kisu, Iori
AU - Iida, Miho
AU - Nakamura, Kanako
AU - Banno, Kouji
AU - Shiraishi, Tetsuro
AU - Tokuoka, Asahi
AU - Yamaguchi, Keigo
AU - Tanaka, Kunio
AU - Iijima, Moito
AU - Senba, Hiroshi
AU - Matsuda, Kiyoko
AU - Hirao, Nobumaru
N1 - Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/12/1
Y1 - 2021/12/1
N2 - Various vaginoplasty procedures have been developed for patients with Mayer–Rokitansky– Küster–Hauser (MRKH) syndrome. Here, we describe a novel laparoscopic vaginoplasty procedure, known as the Kisu modification, using a pull-down technique of the peritoneal flaps with additional structural support to the neovaginal apex using the incised uterine strand in patients with MRKH syndrome. Ten patients with MRKH syndrome (mean age at surgery: 23.9 ± 6.5 years, mean postoperative follow-up period: 17.3 ± 3.7 months) underwent construction of a neovagina via laparoscopic vaginoplasty. All surgeries were performed successfully without complications. The mean neovaginal length at discharge was 10.3 ± 0.5 cm. Anatomical success was achieved in all patients, as two fingers were easily introduced, the neovagina was epithelialized, and the mean neovaginal length was 10.1 ± 1.0 cm 1 year postoperatively. No obliteration, granulation tissue formation at the neovaginal apex, or neovaginal prolapse was recorded. Five of the 10 patients attempted sexual intercourse and all five patients were satisfied with the sexual activity, indicating functional success. Although the number of cases in this case series is few, our favorable experience suggests that the Kisu modification of laparoscopic vaginoplasty procedure is an effective, feasible, and safe approach for neovaginal creation in patients with MRKH syndrome.
AB - Various vaginoplasty procedures have been developed for patients with Mayer–Rokitansky– Küster–Hauser (MRKH) syndrome. Here, we describe a novel laparoscopic vaginoplasty procedure, known as the Kisu modification, using a pull-down technique of the peritoneal flaps with additional structural support to the neovaginal apex using the incised uterine strand in patients with MRKH syndrome. Ten patients with MRKH syndrome (mean age at surgery: 23.9 ± 6.5 years, mean postoperative follow-up period: 17.3 ± 3.7 months) underwent construction of a neovagina via laparoscopic vaginoplasty. All surgeries were performed successfully without complications. The mean neovaginal length at discharge was 10.3 ± 0.5 cm. Anatomical success was achieved in all patients, as two fingers were easily introduced, the neovagina was epithelialized, and the mean neovaginal length was 10.1 ± 1.0 cm 1 year postoperatively. No obliteration, granulation tissue formation at the neovaginal apex, or neovaginal prolapse was recorded. Five of the 10 patients attempted sexual intercourse and all five patients were satisfied with the sexual activity, indicating functional success. Although the number of cases in this case series is few, our favorable experience suggests that the Kisu modification of laparoscopic vaginoplasty procedure is an effective, feasible, and safe approach for neovaginal creation in patients with MRKH syndrome.
KW - Davydov procedure
KW - Mayer–Rokitansky–Küster–Hauser syndrome
KW - Neovagina
KW - Uterine factor infertility
KW - Uterus transplantation
KW - Vaginal agenesis
KW - Vaginoplasty
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U2 - 10.3390/jcm10235510
DO - 10.3390/jcm10235510
M3 - Article
AN - SCOPUS:85119702285
SN - 2077-0383
VL - 10
JO - Journal of Clinical Medicine
JF - Journal of Clinical Medicine
IS - 23
M1 - 5510
ER -