Late-onset type 1 diabetes mellitus in an elderly Japanese woman with single positive insulinoma-associated tyrosine phosphatase-like protein-2 (IA-2) antibody

Masuomi Tomita; Yusuke Kabeya; Yasuaki Yashiro; Toshikatsu Sigihara; Shu Meguro; Yoshihito Atsumi

Late-onset type 1 diabetes mellitus in an elderly Japanese woman with single positive insulinoma-associated tyrosine phosphatase-like protein-2 (IA-2) antibody

Masuomi Tomita, Yusuke Kabeya, Yasuaki Yashiro, Toshikatsu Sigihara, Shu Meguro, Yoshihito Atsumi

Research output: Contribution to journal › Article › peer-review

Abstract

A 79-year-old Japanese old woman hospitalized to assess elevated plasma glucose of 499 mg/dl, HbA1c 6.0%, and positive urine ketone bodies on January 13,2006, had a urinary C peptide concentration of 11.3 μg/day, indicating decreasing insulin secretion. Although antiglutamic acid dehydrogenase (GAD) antibody was negative, she was suspected to have "fulminant type 1 diabetes" due to the rapid onset. She was also diagnosed with autoimmune-related type 1 diabetes mellitus due to high IA-2 antibody (27U/ml). She was treated with insulin during hospitalization. We consider this worth reporting, because very few cases of senile onset type 1 diabetes mellitus are positive for IA-2 antibody.

Original language	English
Pages (from-to)	245-249
Number of pages	5
Journal	Journal of the Japan Diabetes Society
Volume	51
Issue number	3
Publication status	Published - 2008 Jun 2
Externally published	Yes

ASJC Scopus subject areas

Internal Medicine
Endocrinology, Diabetes and Metabolism
Endocrinology

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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Late-onset type 1 diabetes mellitus in an elderly Japanese woman with single positive insulinoma-associated tyrosine phosphatase-like protein-2 (IA-2) antibody. / Tomita, Masuomi; Kabeya, Yusuke; Yashiro, Yasuaki et al.
In: Journal of the Japan Diabetes Society, Vol. 51, No. 3, 02.06.2008, p. 245-249.

Research output: Contribution to journal › Article › peer-review

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AU - Sigihara, Toshikatsu

AU - Meguro, Shu

AU - Atsumi, Yoshihito

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Late-onset type 1 diabetes mellitus in an elderly Japanese woman with single positive insulinoma-associated tyrosine phosphatase-like protein-2 (IA-2) antibody

Abstract

ASJC Scopus subject areas

UN SDGs

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