Left frontotemporal hyperperfusion in a patient with post-stroke mania

Masaru Mimura, Kazuyuki Nakagome, Natsuko Hirashima, Hiroshi Ishiwata, Kunitoshi Kamijima, Akira Shinozuka, Hiroshi Matsuda

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)


A 78-year-old housewife with major depression developed a right-sided infarction in the territory of the middle cerebral arteries, followed by acute post-stroke mania. Comparison between pre- and post-stroke SPECT scans demonstrated a unique pattern of left orbitofrontal hyperperfusion with extensive right frontal hypoperfusion. A functional imbalance between right and left orbitofrontal cortices may be important in mania.

Original languageEnglish
Pages (from-to)263-267
Number of pages5
JournalPsychiatry Research - Neuroimaging
Issue number3
Publication statusPublished - 2005 Aug 30
Externally publishedYes


  • Mood disorder
  • Orbitofrontal cortex
  • Single photon emission tomography

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Radiology Nuclear Medicine and imaging
  • Psychiatry and Mental health


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