Lifestyle factors and visible skin aging in a population of Japanese elders

Keiko Asakura, Yuji Nishiwaki, Ai Milojevic, Takehiro Michikawa, Yuriko Kikuchi, Makiko Nakano, Satoko Iwasawa, Greg Hillebrand, Kukizo Miyamoto, Masaji Ono, Yoshihide Kinjo, Suminori Akiba, Toru Takebayashi

Research output: Contribution to journalArticlepeer-review

33 Citations (Scopus)


Background: The number of studies that use objective and quantitative methods to evaluate facial skin aging in elderly people is extremely limited, especially in Japan. Therefore, in this cross-sectional study we attempted to characterize the condition of facial skin (hyperpigmentation, pores, texture, and wrinkling) in Japanese adults aged 65 years or older by using objective and quantitative imaging methods. In addition, we aimed to identify lifestyle factors significantly associated with these visible signs of aging. Methods: The study subjects were 802 community-dwelling Japanese men and women aged at least 65 years and living in the town of Kurabuchi (Takasaki City, Gunma Prefecture, Japan), a mountain community with a population of approximately 4800. The facial skin condition of subjects was assessed quantitatively using a standardized facial imaging system and subsequent computer image analysis. Lifestyle information was collected using a structured questionnaire. The association between skin condition and lifestyle factors was examined using multivariable regression analysis. Results: Among women, the mean values for facial texture, hyperpigmentation, and pores were generally lower than those among age-matched men. There was no significant difference between sexes in the severity of facial wrinkling. Older age was associated with worse skin condition among women only. After adjusting for age, smoking status and topical sun protection were significantly associated with skin condition among both men and women. Conclusions: Our study revealed significant differences between sexes in the severity of hyperpigmentation, texture, and pores, but not wrinkling. Smoking status and topical sun protection were significantly associated with signs of visible skin aging in this study population.

Original languageEnglish
Pages (from-to)251-259
Number of pages9
JournalJournal of epidemiology
Issue number5
Publication statusPublished - 2009 Aug


  • Japan
  • Lifestyle
  • Older adults
  • Quantitative method
  • Skin aging

ASJC Scopus subject areas

  • Epidemiology


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