Localization of the human gene for 230-kDal bullous pemphigoid autoantigen (BPAG1) to chromosome 6pter-→q15

S. Minoshima; M. Amagai; J. Kudoh; R. Fukuyama; T. Hashimoto; T. Nishikawa; N. Shimizu

doi:10.1159/000133108

Localization of the human gene for 230-kDal bullous pemphigoid autoantigen (BPAG1) to chromosome 6pter-→q15

S. Minoshima, M. Amagai, J. Kudoh, R. Fukuyama, T. Hashimoto, T. Nishikawa, N. Shimizu

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Abstract

Chromosome mapping of the human gene encoding the 230-kDal autoantigen of an autoimmune skin disease, bullous pemphigoid, was performed using flow-sorted human chromosomes of cells of normal karyotype and cells carrying a reciprocal translocation t(6;16)(q15;q24). The cDNA of the autoantigen hybridized with intact chromosome 6 and translocation chromosome 6p-(6pter-→q15::16q24-→qter). The gene (BPA230) was located to the chromosome region 6pter-→q 15.

Original language	English
Pages (from-to)	30-32
Number of pages	3
Journal	Cytogenetics and Cell Genetics
Volume	57
Issue number	1
DOIs	https://doi.org/10.1159/000133108
Publication status	Published - 1991

ASJC Scopus subject areas

Genetics
Cell Biology

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abstract = "Chromosome mapping of the human gene encoding the 230-kDal autoantigen of an autoimmune skin disease, bullous pemphigoid, was performed using flow-sorted human chromosomes of cells of normal karyotype and cells carrying a reciprocal translocation t(6;16)(q15;q24). The cDNA of the autoantigen hybridized with intact chromosome 6 and translocation chromosome 6p-(6pter-→q15::16q24-→qter). The gene (BPA230) was located to the chromosome region 6pter-→q 15.",

author = "S. Minoshima and M. Amagai and J. Kudoh and R. Fukuyama and T. Hashimoto and T. Nishikawa and N. Shimizu",

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doi = "10.1159/000133108",

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AU - Minoshima, S.

AU - Amagai, M.

AU - Kudoh, J.

AU - Fukuyama, R.

AU - Hashimoto, T.

AU - Nishikawa, T.

AU - Shimizu, N.

PY - 1991

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N2 - Chromosome mapping of the human gene encoding the 230-kDal autoantigen of an autoimmune skin disease, bullous pemphigoid, was performed using flow-sorted human chromosomes of cells of normal karyotype and cells carrying a reciprocal translocation t(6;16)(q15;q24). The cDNA of the autoantigen hybridized with intact chromosome 6 and translocation chromosome 6p-(6pter-→q15::16q24-→qter). The gene (BPA230) was located to the chromosome region 6pter-→q 15.

AB - Chromosome mapping of the human gene encoding the 230-kDal autoantigen of an autoimmune skin disease, bullous pemphigoid, was performed using flow-sorted human chromosomes of cells of normal karyotype and cells carrying a reciprocal translocation t(6;16)(q15;q24). The cDNA of the autoantigen hybridized with intact chromosome 6 and translocation chromosome 6p-(6pter-→q15::16q24-→qter). The gene (BPA230) was located to the chromosome region 6pter-→q 15.

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Localization of the human gene for 230-kDal bullous pemphigoid autoantigen (BPAG1) to chromosome 6pter-→q15

Abstract

ASJC Scopus subject areas

UN SDGs

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