@inproceedings{ebcc2915938d441bba3f138e14326dcf,
title = "Long-term implantation of primary islet cell-encapsulating hydrogel microfibers in diabetic mice",
abstract = "This paper describes long-term implantation of primary pancreatic islet cell fibers into diabetic mice. Primary rat pancreatic islet cells were encapsulated in core-shell hydrogel microfibers and implanted into renal capsular space of diabetic mice by using a microcatheter. The blood glucose concentration of the recipient mice were normalized for more than 36 days. This result shows that our cell fiber approach can be applied to long-term implantation and can provide primary islet cells with sufficient microenvironment to promote cellular functions in vivo.",
keywords = "Cell encapsulation, Diabetes mellitus, Hydrogel, Implantation, Microfiber",
author = "Hiroaki Onoe and Teru Okitsu and Akane Itou and Shoji Takeuchi",
year = "2013",
month = jan,
day = "1",
language = "English",
isbn = "9781632666246",
series = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013",
publisher = "Chemical and Biological Microsystems Society",
pages = "1836--1838",
booktitle = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013",
note = "17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 ; Conference date: 27-10-2013 Through 31-10-2013",
}
