Loss of flagellation in dnaA mutants of Escherichia coli

T. Mizushima, A. Tomura, T. Shinpuku, T. Miki, K. Sekimizu

Research output: Contribution to journalComment/debatepeer-review

38 Citations (Scopus)


A dnaA46 mutant of Escherichia coli showed loss of motility at 37°C, a permissive temperature for cell growth of this mutant. Other dnaA mutations near the middle of the gene also caused an immotile phenotype. The amount of flagellin was much less in the dnaA46 mutant than in the wild-type control, as was the promoter activity. DnaA protein may play an important role in expression of the fliC gene.

Original languageEnglish
Pages (from-to)5544-5546
Number of pages3
JournalJournal of Bacteriology
Issue number17
Publication statusPublished - 1994
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology


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