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Mannich-type allylic C-H functionalization of enol silyl ethers under photoredox-thiol hybrid catalysis

Research output: Contribution to journal › Article › peer-review

Abstract

The synergy of an Ir-based photosensitizer with mild oxidizing ability and a thiol catalyst enables efficient allylic C-H functionalization of enol silyl ethers with imines under visible light irradiation. Subsequent transformations of the aminoalkylated enol silyl ethers allow for the facile construction of unique molecular frameworks such as functionalized octahydroisoindol-4-one.

Original languageEnglish
Pages (from-to)141-145
Number of pages5
JournalOrganic and Biomolecular Chemistry
Volume19
Issue number1
DOIs
Publication statusPublished - 2021 Jan 7
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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