Masked Isolated Nocturnal Hypertension in Children and Young Adults

Hisayo Fujita, Seiji Matsuoka, Midori Awazu

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)


Isolated nocturnal hypertension (INH) is characterized by normal daytime blood pressure (BP) and elevated nighttime BP diagnosed by ambulatory BP monitoring. Masked isolated nocturnal hypertension (MINH) is a subtype of INH in which office BP is normal. We studied the frequency and characteristics of INH and MINH in children and young adults. One hundred and ninety-eight subjects seen by the pediatric nephrology service were studied retrospectively. Isolated nocturnal hypertension (INH) and MINH were diagnosed according to daytime and nighttime ABP and office BP in the case of the latter. One hundred and eighteen subjects (60%) had normotension, 6 (3%) had isolated daytime hypertension, 32 (16%) had INH, and 42 (21%) had day–night hypertension. Sixteen subjects had MINH (8.1%). The underlying diseases of MINH were as follows: no underlying disease 9 (56%), renal disease 6 (38%), and endocrine disease 1 (6%). There was no significant difference in the underlying disease, gender, age, and BMI between MINH and INH with elevated office BP. In conclusion, MINH is present in children and young adults. Since there were no specific features for MINH, screening with ambulatory or home BP monitoring during sleep may be appropriate.

Original languageEnglish
Pages (from-to)66-70
Number of pages5
JournalPediatric Cardiology
Issue number1
Publication statusPublished - 2018 Jan 1


  • Ambulatory blood pressure monitoring
  • Children
  • Isolated nocturnal hypertension
  • Masked isolated nocturnal hypertension
  • Nighttime blood pressure
  • Target organ damage

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Cardiology and Cardiovascular Medicine


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