TY - JOUR
T1 - Maternal speech shapes the cerebral frontotemporal network in neonates
T2 - A hemodynamic functional connectivity study
AU - Uchida-Ota, Mariko
AU - Arimitsu, Takeshi
AU - Tsuzuki, Daisuke
AU - Dan, Ippeita
AU - Ikeda, Kazushige
AU - Takahashi, Takao
AU - Minagawa, Yasuyo
N1 - Funding Information:
This work was supported by the Global COE (Center of Excellence) program of Keio University and the Japan Society for the Promotion of Science (JSPS) Kakenhi (Grant Nos. 15H01691 , 19H05594 , 24791123 , 24591609 , and 15K09725 ).
Publisher Copyright:
© 2019 The Authors
PY - 2019/10
Y1 - 2019/10
N2 - Language development and the capacity for communication in infants are predominantly supported by their mothers, beginning when infants are still in utero. Although a mother's speech should thus have a significant impact on her neonate's brain, neurocognitive evidence for this hypothesis remains elusive. The present study examined 37 neonates using near-infrared spectroscopy and observed the interactions between multiple cortical regions while neonates heard speech spoken by their mothers or by strangers. We analyzed the functional connectivity between regions whose response-activation patterns differed between the two types of speakers. We found that when hearing their mothers’ speech, functional connectivity was enhanced in both the neonatal left and right frontotemporal networks. On the left it was enhanced between the inferior/middle frontal gyrus and the temporal cortex, while on the right it was enhanced between the frontal pole and temporal cortex. In particular, the frontal pole was more strongly connected to the left supramarginal area when hearing speech from mothers. These enhanced frontotemporal networks connect areas that are associated with language (left) and voice processing (right) at later stages of development. We suggest that these roles are initially fostered by maternal speech.
AB - Language development and the capacity for communication in infants are predominantly supported by their mothers, beginning when infants are still in utero. Although a mother's speech should thus have a significant impact on her neonate's brain, neurocognitive evidence for this hypothesis remains elusive. The present study examined 37 neonates using near-infrared spectroscopy and observed the interactions between multiple cortical regions while neonates heard speech spoken by their mothers or by strangers. We analyzed the functional connectivity between regions whose response-activation patterns differed between the two types of speakers. We found that when hearing their mothers’ speech, functional connectivity was enhanced in both the neonatal left and right frontotemporal networks. On the left it was enhanced between the inferior/middle frontal gyrus and the temporal cortex, while on the right it was enhanced between the frontal pole and temporal cortex. In particular, the frontal pole was more strongly connected to the left supramarginal area when hearing speech from mothers. These enhanced frontotemporal networks connect areas that are associated with language (left) and voice processing (right) at later stages of development. We suggest that these roles are initially fostered by maternal speech.
KW - Familiarity
KW - Frontotemporal network
KW - Functional near-infrared spectroscopy
KW - Mother's voice recognition
KW - Neonate
KW - Phase-Locking value
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U2 - 10.1016/j.dcn.2019.100701
DO - 10.1016/j.dcn.2019.100701
M3 - Article
C2 - 31513977
AN - SCOPUS:85071891759
SN - 1878-9293
VL - 39
JO - Developmental Cognitive Neuroscience
JF - Developmental Cognitive Neuroscience
M1 - 100701
ER -