Microfluidic handling of hydrogel microfibers

H. Onoe; R. Gojo; K. Kuribayashi-Shigetomi; S. Takeuchi

doi:10.1109/MEMSYS.2012.6170255

Microfluidic handling of hydrogel microfibers

H. Onoe, R. Gojo, K. Kuribayashi-Shigetomi, S. Takeuchi

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

3 Citations (Scopus)

Abstract

This paper describes a handling method of thin (∼200 μm in diameter), long (>meter) and fragile (breaking point: ∼2 μN) hydrogel microfibers in liquid. By using fluid flow and thin capillary, the hydrogel fibers can be manipulated, clamped and cut without damaging and entangling the hydrogel microfibers (we termed "microfluidic handling"). This microfluidic handling technique enables us to construct a mechanical weaving machine for cell-encapsulating hydrogel microfibers, resulting the construction of centimeter-scale woven 3D cellular structures. In addition, we demonstrated computer-controlled automatic handling of the hydrogel microfibers, indicating that the microfluidic handling would be a fundamental technique for rapid and reliable handling of fragile hydrogel microfibers containing various types of functional materials such as cells, bacteria, proteins and nanofibers.

Original language	English
Title of host publication	2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012
Pages	1065-1068
Number of pages	4
DOIs	https://doi.org/10.1109/MEMSYS.2012.6170255
Publication status	Published - 2012 May 7
Externally published	Yes
Event	2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012 - Paris, France Duration: 2012 Jan 29 → 2012 Feb 2

Publication series

Name	Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN (Print)	1084-6999

Other

Other	2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012
Country/Territory	France
City	Paris
Period	12/1/29 → 12/2/2

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Mechanical Engineering
Electrical and Electronic Engineering

Access to Document

10.1109/MEMSYS.2012.6170255

Cite this

Onoe, H., Gojo, R., Kuribayashi-Shigetomi, K., & Takeuchi, S. (2012). Microfluidic handling of hydrogel microfibers. In 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012 (pp. 1065-1068). Article 6170255 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)). https://doi.org/10.1109/MEMSYS.2012.6170255

Microfluidic handling of hydrogel microfibers. / Onoe, H.; Gojo, R.; Kuribayashi-Shigetomi, K. et al.
2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012. 2012. p. 1065-1068 6170255 (Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Onoe, H, Gojo, R, Kuribayashi-Shigetomi, K & Takeuchi, S 2012, Microfluidic handling of hydrogel microfibers. in 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012., 6170255, Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), pp. 1065-1068, 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems, MEMS 2012, Paris, France, 12/1/29. https://doi.org/10.1109/MEMSYS.2012.6170255

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Microfluidic handling of hydrogel microfibers

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