Microscopic polyangiitis diagnosed by muscle specimen: a case report and literature review

Okinori Murata; Keisuke Izumi; Yuko Kaneko; Hidekata Yasuoka; Katsuya Suzuki; Shiro Matsubara; Kunihiro Yamaoka; Tsutomu Takeuchi

doi:10.1080/24725625.2018.1429804

Microscopic polyangiitis diagnosed by muscle specimen: a case report and literature review

Okinori Murata, Keisuke Izumi, Yuko Kaneko, Hidekata Yasuoka, Katsuya Suzuki, Shiro Matsubara, Kunihiro Yamaoka, Tsutomu Takeuchi

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

We describe the case of a 76-year-old man with microscopic polyangiitis (MPA) presenting with myalgia, abnormal muscle MRI findings and pulmonary fibrosis. Although he had been initially suspected of polymyositis, laboratory tests of normal myogenic enzymes and positive myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA) and muscle specimen showing vasculitis without myogenic changes led to the diagnosis of MPA. This case indicates that ANCA-associated vasculitis is an important differential diagnosis in patients with muscle involvement and interstitial lung disease.

Original language	English
Pages (from-to)	181-184
Number of pages	4
Journal	Modern Rheumatology Case Reports
Volume	2
Issue number	2
DOIs	https://doi.org/10.1080/24725625.2018.1429804
Publication status	Published - 2018 Jul 3

Keywords

Alveolar hemorrhage
microscopic polyangiitis
muscle biopsy
myopathy
pulmonary fibrosis

ASJC Scopus subject areas

Rheumatology

Access to Document

10.1080/24725625.2018.1429804

Cite this

@article{98a2c4bf0cae4dd88a604a6bcd66d179,

title = "Microscopic polyangiitis diagnosed by muscle specimen: a case report and literature review",

abstract = "We describe the case of a 76-year-old man with microscopic polyangiitis (MPA) presenting with myalgia, abnormal muscle MRI findings and pulmonary fibrosis. Although he had been initially suspected of polymyositis, laboratory tests of normal myogenic enzymes and positive myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA) and muscle specimen showing vasculitis without myogenic changes led to the diagnosis of MPA. This case indicates that ANCA-associated vasculitis is an important differential diagnosis in patients with muscle involvement and interstitial lung disease.",

keywords = "Alveolar hemorrhage, microscopic polyangiitis, muscle biopsy, myopathy, pulmonary fibrosis",

author = "Okinori Murata and Keisuke Izumi and Yuko Kaneko and Hidekata Yasuoka and Katsuya Suzuki and Shiro Matsubara and Kunihiro Yamaoka and Tsutomu Takeuchi",

note = "Publisher Copyright: {\textcopyright} 2018, {\textcopyright} 2018 Japan College of Rheumatology.",

year = "2018",

month = jul,

day = "3",

doi = "10.1080/24725625.2018.1429804",

language = "English",

volume = "2",

pages = "181--184",

journal = "Modern Rheumatology Case Reports",

issn = "2472-5625",

publisher = "Oxford University Press",

number = "2",

}

TY - JOUR

T1 - Microscopic polyangiitis diagnosed by muscle specimen

T2 - a case report and literature review

AU - Murata, Okinori

AU - Izumi, Keisuke

AU - Kaneko, Yuko

AU - Yasuoka, Hidekata

AU - Suzuki, Katsuya

AU - Matsubara, Shiro

AU - Yamaoka, Kunihiro

AU - Takeuchi, Tsutomu

PY - 2018/7/3

Y1 - 2018/7/3

N2 - We describe the case of a 76-year-old man with microscopic polyangiitis (MPA) presenting with myalgia, abnormal muscle MRI findings and pulmonary fibrosis. Although he had been initially suspected of polymyositis, laboratory tests of normal myogenic enzymes and positive myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA) and muscle specimen showing vasculitis without myogenic changes led to the diagnosis of MPA. This case indicates that ANCA-associated vasculitis is an important differential diagnosis in patients with muscle involvement and interstitial lung disease.

AB - We describe the case of a 76-year-old man with microscopic polyangiitis (MPA) presenting with myalgia, abnormal muscle MRI findings and pulmonary fibrosis. Although he had been initially suspected of polymyositis, laboratory tests of normal myogenic enzymes and positive myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA) and muscle specimen showing vasculitis without myogenic changes led to the diagnosis of MPA. This case indicates that ANCA-associated vasculitis is an important differential diagnosis in patients with muscle involvement and interstitial lung disease.

KW - Alveolar hemorrhage

KW - microscopic polyangiitis

KW - muscle biopsy

KW - myopathy

KW - pulmonary fibrosis

UR - http://www.scopus.com/inward/record.url?scp=85103015577&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85103015577&partnerID=8YFLogxK

U2 - 10.1080/24725625.2018.1429804

DO - 10.1080/24725625.2018.1429804

M3 - Article

AN - SCOPUS:85103015577

SN - 2472-5625

VL - 2

SP - 181

EP - 184

JO - Modern Rheumatology Case Reports

JF - Modern Rheumatology Case Reports

IS - 2

ER -

Microscopic polyangiitis diagnosed by muscle specimen: a case report and literature review

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this