TY - GEN
T1 - Modeling of influence of frontal sinus on NIRS signal of brain activation
AU - Yamamoto, Daisuke
AU - Kuroda, Shoko
AU - Okada, Eiji
PY - 2007/1/1
Y1 - 2007/1/1
N2 - In the brain activation measurements by near infrared spectroscopy (NIRS), the partial optical path length in the brain, which is an index of the sensitivity of the NIRS signal to the brain activation, is strongly affected by the thickness and the structure of the superficial tissues. In this study, we investigate the influence of the frontal sinus on the NIRS signal of the brain activation. The light propagation in a simplified head model including a void region mimicking the frontal sinus is predicted by Monte Carlo simulation to investigate the influence of the frontal sinus on the partial optical path length in the brain and the mean optical path length in the head. The frontal sinus strongly affects the light propagation in the head. The partial optical path length for small source-detector separation tends to be increased by the presence of the frontal sinus whereas that for large source-detector separation is decreased by the influence of the frontal sinus.
AB - In the brain activation measurements by near infrared spectroscopy (NIRS), the partial optical path length in the brain, which is an index of the sensitivity of the NIRS signal to the brain activation, is strongly affected by the thickness and the structure of the superficial tissues. In this study, we investigate the influence of the frontal sinus on the NIRS signal of the brain activation. The light propagation in a simplified head model including a void region mimicking the frontal sinus is predicted by Monte Carlo simulation to investigate the influence of the frontal sinus on the partial optical path length in the brain and the mean optical path length in the head. The frontal sinus strongly affects the light propagation in the head. The partial optical path length for small source-detector separation tends to be increased by the presence of the frontal sinus whereas that for large source-detector separation is decreased by the influence of the frontal sinus.
KW - Brain activation measurement
KW - Frontal sinus
KW - Near infrared spectroscopy
KW - Partial optical path length
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M3 - Conference contribution
SN - 9780819467713
T3 - Optics InfoBase Conference Papers
BT - European Conference on Biomedical Optics, ECBO 2007
PB - Optical Society of America
T2 - European Conference on Biomedical Optics, ECBO 2007
Y2 - 17 June 2007 through 17 June 2007
ER -