Molecular mechanism of congenital heart disease and pulmonary hypertension

Toshio Nakanishi, H. Scott Baldwin, Jeffrey R. Fineman, Hiroyuki Yamagishi

Research output: Book/ReportBook

1 Citation (Scopus)


Introduction This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, growth factors, transcription factors and cellular interactions, as well as stem cell engineering technologies. The book also presents recent advances in our understanding of the molecular mechanism of lung development, pulmonary hypertension and molecular regulation of the ductus arteriosus. As such, it is an ideal resource for physicians, scientists and investigators interested in the latest findings on the origins of congenital heart disease and potential future therapies involving pulmonary circulation/hypertension and the ductus arteriosus.

Original languageEnglish
PublisherSpringer Singapore
Number of pages405
ISBN (Electronic)9789811511851
ISBN (Print)9789811511844
Publication statusPublished - 2020 Jan 1


  • Cellular interactions
  • Ductus arteriosus
  • Heart
  • Lung
  • Molecular mechanisms
  • Open access
  • Pulmonary circulation
  • Stem cell engineering

ASJC Scopus subject areas

  • Medicine(all)


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