Monoamine oxidase genes polymorphisms and mood disorder

Taro Muramatsu; Sachio Matsushita; Shigenobu Kanba; Susumu Higuchi; Hiroshi Manki; Eiji Suzuki; Masahiro Asai

doi:10.1002/(SICI)1096-8628(19970919)74:5<494::AID-AJMG7>3.0.CO;2-O

Monoamine oxidase genes polymorphisms and mood disorder

Taro Muramatsu, Sachio Matsushita, Shigenobu Kanba, Susumu Higuchi, Hiroshi Manki, Eiji Suzuki, Masahiro Asai

Research output: Contribution to journal › Article › peer-review

38 Citations (Scopus)

Abstract

We investigated a genetic association between mood disorders (bipolar and unipolar) and the alleles of monoamine oxidase (MAO) A and B (MAOA and MAOB). One hundred and twelve unrelated Japanese patients (60 bipolar, 52 unipolar) and 100 controls were genotyped for three markers of MAOA and for one marker of MAOB. No statistically significant difference in the distribution of the alleles existed between cases and controls. Therefore, our results did not support the involvement of the alleles at MAOA and MAOB in the etiology of mood disorder.

Original language	English
Pages (from-to)	494-496
Number of pages	3
Journal	American Journal of Medical Genetics - Neuropsychiatric Genetics
Volume	74
Issue number	5
DOIs	https://doi.org/10.1002/(SICI)1096-8628(19970919)74:5<494::AID-AJMG7>3.0.CO;2-O
Publication status	Published - 1997
Externally published	Yes

Keywords

Gene polymorphism
Monamine oxidase
Mood disorder

ASJC Scopus subject areas

Genetics(clinical)
Psychiatry and Mental health
Cellular and Molecular Neuroscience

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/(SICI)1096-8628(19970919)74:5<494::AID-AJMG7>3.0.CO;2-O

Cite this

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title = "Monoamine oxidase genes polymorphisms and mood disorder",

abstract = "We investigated a genetic association between mood disorders (bipolar and unipolar) and the alleles of monoamine oxidase (MAO) A and B (MAOA and MAOB). One hundred and twelve unrelated Japanese patients (60 bipolar, 52 unipolar) and 100 controls were genotyped for three markers of MAOA and for one marker of MAOB. No statistically significant difference in the distribution of the alleles existed between cases and controls. Therefore, our results did not support the involvement of the alleles at MAOA and MAOB in the etiology of mood disorder.",

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T1 - Monoamine oxidase genes polymorphisms and mood disorder

AU - Muramatsu, Taro

AU - Matsushita, Sachio

AU - Kanba, Shigenobu

AU - Higuchi, Susumu

AU - Manki, Hiroshi

AU - Suzuki, Eiji

AU - Asai, Masahiro

PY - 1997

Y1 - 1997

N2 - We investigated a genetic association between mood disorders (bipolar and unipolar) and the alleles of monoamine oxidase (MAO) A and B (MAOA and MAOB). One hundred and twelve unrelated Japanese patients (60 bipolar, 52 unipolar) and 100 controls were genotyped for three markers of MAOA and for one marker of MAOB. No statistically significant difference in the distribution of the alleles existed between cases and controls. Therefore, our results did not support the involvement of the alleles at MAOA and MAOB in the etiology of mood disorder.

AB - We investigated a genetic association between mood disorders (bipolar and unipolar) and the alleles of monoamine oxidase (MAO) A and B (MAOA and MAOB). One hundred and twelve unrelated Japanese patients (60 bipolar, 52 unipolar) and 100 controls were genotyped for three markers of MAOA and for one marker of MAOB. No statistically significant difference in the distribution of the alleles existed between cases and controls. Therefore, our results did not support the involvement of the alleles at MAOA and MAOB in the etiology of mood disorder.

KW - Gene polymorphism

KW - Monamine oxidase

KW - Mood disorder

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Monoamine oxidase genes polymorphisms and mood disorder

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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