Abstract
The scattering of tissue causes the ambiguity of volume of tissue interrogated by near infrared spectroscopy (NIRS) instruments. The sampling volume, which is the volume of tissue interrogated by NIRS instrument with CW light, can be predicted by calculating the distribution of light which arrives the detector. Recently, time-resolved and frequency modulated measurements has been applied to near-infrared spectroscopy (NIRS) instruments. Although the volume of tissue interrogated by the measurements of mean time, phase and so forth may be different from that by CW intensity measurement, there are very few studies on the volume of tissue interrogated by time-resolved and frequency domain measurements. In this study a Monte Carlo algorithm to predict the volume of tissue interrogated by mean time measurements is proposed and is applied to homogeneous and layered models. The volume of tissue interrogated by mean time measurement is significantly different from the sampling volume.
| Original language | English |
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| Pages (from-to) | 20-27 |
| Number of pages | 8 |
| Journal | Proceedings of SPIE - The International Society for Optical Engineering |
| Volume | 3566 |
| Publication status | Published - 1999 Jan 1 |
| Event | Proceedings of the 1998 Photon Propagation in Tissues IV - Stockholm, SWE Duration: 1998 Sept 9 → 1998 Sept 11 |
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Computer Science Applications
- Applied Mathematics
- Electrical and Electronic Engineering