Abstract
The optical coherence tomography (OCT) has been successfully applied to diagnostic imaging of transparent ocular organs. In case of highly scattering tissues such as skin and mucous membrane, and the OCT signal includes noise component due to multiple scattering in tissue, the characteristics of the OCT signal from the highly scattering tissue is more complex. In this study, we investigate the characteristics of the OCT signal from the low-scattering and highly scattering tissues by Monte Carlo simulation. In case of low-scattering tissue, the intensity of the signal is maximised when the focal depth equals the probing depth and the spurious peak of the noise due to scattering is observed at the focal depth in the OCT image. In case of highly scattering tissue, the intensity of the signal is maximised when the focal depth is smaller than the probing depth and the noise is almost independent of the focal depth.
| Original language | English |
|---|---|
| Pages (from-to) | 190-197 |
| Number of pages | 8 |
| Journal | Proceedings of SPIE - The International Society for Optical Engineering |
| Volume | 5138 |
| DOIs | |
| Publication status | Published - 2003 |
| Event | Photon Migration and Diffuse-Light Imaging - Munich, Germany Duration: 2003 Jun 22 → 2003 Jun 23 |
Keywords
- Optical coherence tomography
- Optical property mismatch
- Photon migration in tissue
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Computer Science Applications
- Applied Mathematics
- Electrical and Electronic Engineering