Nematocidal Principles In “Oakmoss Absolute” and Nematocidal Activity of 2,4-Dihydroxybenzoates

Kaoru Kondo; Toshiya Sato; Ali Mohammad Ahad; Yoshihisa Goto; Fumiyuki Kiuchi; Yoshisuke Tsuda

doi:10.1248/cpb.39.1043

Nematocidal Principles In “Oakmoss Absolute” and Nematocidal Activity of 2,4-Dihydroxybenzoates

Kaoru Kondo, Toshiya Sato, Ali Mohammad Ahad, Yoshihisa Goto, Fumiyuki Kiuchi, Yoshisuke Tsuda

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

Abstract

Nematocidal principles obtained from oakmoss absolute were identified as methyl 2,4-dihydroxy-3,6-di-methylbenzoate (2), ethyl 3-formyl-2,4-dihydroxy-6-methylbenzoate (4), and ethyl 5-chloro-3-formyl-2,4-dihydroxy-6-methylbenzoate (7). In relation to their structures, the nematocidal activity of 2,4-dihydroxybenzoates of methyl to tetradecyl was tested and the strongest activity was found in the octyl ester (minimal lethal concentration = 13 μm).

Original language	English
Pages (from-to)	1043-1046
Number of pages	4
Journal	Chemical and Pharmaceutical Bulletin
Volume	39
Issue number	4
DOIs	https://doi.org/10.1248/cpb.39.1043
Publication status	Published - 1991
Externally published	Yes

Keywords

Evernia prunastri
Toxocara canis
dihydroxybenzoate
nematocidal activity
oakmoss absolute
octyl 2,4-dihydroxybenzoate
structure-activity relationship

ASJC Scopus subject areas

General Chemistry
Drug Discovery

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10.1248/cpb.39.1043

Cite this

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title = "Nematocidal Principles In “Oakmoss Absolute” and Nematocidal Activity of 2,4-Dihydroxybenzoates",

abstract = "Nematocidal principles obtained from oakmoss absolute were identified as methyl 2,4-dihydroxy-3,6-di-methylbenzoate (2), ethyl 3-formyl-2,4-dihydroxy-6-methylbenzoate (4), and ethyl 5-chloro-3-formyl-2,4-dihydroxy-6-methylbenzoate (7). In relation to their structures, the nematocidal activity of 2,4-dihydroxybenzoates of methyl to tetradecyl was tested and the strongest activity was found in the octyl ester (minimal lethal concentration = 13 μm).",

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author = "Kaoru Kondo and Toshiya Sato and Ahad, {Ali Mohammad} and Yoshihisa Goto and Fumiyuki Kiuchi and Yoshisuke Tsuda",

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T1 - Nematocidal Principles In “Oakmoss Absolute” and Nematocidal Activity of 2,4-Dihydroxybenzoates

AU - Kondo, Kaoru

AU - Sato, Toshiya

AU - Ahad, Ali Mohammad

AU - Goto, Yoshihisa

AU - Kiuchi, Fumiyuki

AU - Tsuda, Yoshisuke

PY - 1991

Y1 - 1991

N2 - Nematocidal principles obtained from oakmoss absolute were identified as methyl 2,4-dihydroxy-3,6-di-methylbenzoate (2), ethyl 3-formyl-2,4-dihydroxy-6-methylbenzoate (4), and ethyl 5-chloro-3-formyl-2,4-dihydroxy-6-methylbenzoate (7). In relation to their structures, the nematocidal activity of 2,4-dihydroxybenzoates of methyl to tetradecyl was tested and the strongest activity was found in the octyl ester (minimal lethal concentration = 13 μm).

AB - Nematocidal principles obtained from oakmoss absolute were identified as methyl 2,4-dihydroxy-3,6-di-methylbenzoate (2), ethyl 3-formyl-2,4-dihydroxy-6-methylbenzoate (4), and ethyl 5-chloro-3-formyl-2,4-dihydroxy-6-methylbenzoate (7). In relation to their structures, the nematocidal activity of 2,4-dihydroxybenzoates of methyl to tetradecyl was tested and the strongest activity was found in the octyl ester (minimal lethal concentration = 13 μm).

KW - Evernia prunastri

KW - Toxocara canis

KW - dihydroxybenzoate

KW - nematocidal activity

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KW - structure-activity relationship

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Nematocidal Principles In “Oakmoss Absolute” and Nematocidal Activity of 2,4-Dihydroxybenzoates

Abstract

Keywords

ASJC Scopus subject areas

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