New strategy for catalytic oxidative CH functionalization: Efficient combination of transition-metal catalyst and electrochemical oxidation

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Abstract

Transition-metal-catalyzed CH functionalizations have been extensively studied as atom- and step-economical methods in organic synthesis. Oxidative CH functionalization is one of the most extensively studied reactions in this area, but it is often necessary to deactivate the remaining oxidants and to remove the wastes derived from chemical oxidants. During the past few years, a combination of transition-metal-catalyzed CH activation and electrochemical oxidation has become a commonly-used environmentally-benign strategy for catalytic oxidative CH functionalization. In this review, we briefly survey studies regarding the transition-metal-catalyzed oxidative CH functionalization with the aid of electrochemical oxidation.

Original languageEnglish
Pages (from-to)1256-1269
Number of pages14
JournalChemistry Letters
Volume49
Issue number10
DOIs
Publication statusPublished - 2020 Oct

Keywords

  • C-H activation
  • Electrochemical reaction
  • Regioselective functionalization

ASJC Scopus subject areas

  • Chemistry(all)

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