New trends in near-infrared fluorophores for bioimaging

Keitaro Umezawa, Daniel Citterio, Koji Suzuki

Research output: Contribution to journalReview articlepeer-review

151 Citations (Scopus)


This review summarizes progress in the field of near-infrared (NIR) fluorophores achieved during the last decade from the viewpoint of chemistry. Those compounds are of wide interest in bioanalysis and bioimaging, such as in vivo fluorescence imaging. Particular focus is placed on the recent developments of BODIPY and rhodamine derivatives, which belong to the most evolved NIR fluorophores. The data compiled in this review, including the chemical structures and optical properties of all compounds introduced, provide readers of this article with an overview of the field of NIR fluorophores.

Original languageEnglish
Pages (from-to)327-349
Number of pages23
Journalanalytical sciences
Issue number3
Publication statusPublished - 2014 Mar


  • Boron dipyrromethene
  • Cyanine
  • Fluorescent imaging
  • Fluorescent sensor
  • Molecular imaging
  • Near-infrared fluorescent probe
  • Near-infrared fluorophore
  • Rhodamine
  • Squaraine

ASJC Scopus subject areas

  • Analytical Chemistry


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