N,N-dimethylformamide (dmf) vapor absorption through the skin in workers

Hiroyuki Miyauchi, Shigeru Tanaka, Tetsuo Nomiyama, Yukio Seki, Shun'ichiro Imamiya, Kazuyuki Omae

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


N,N-Dimethylformamide (DMF, CAS 68-12-2) is known to be one of the water-soluble organic solvents with a markedly high skin absorption rate. In volunteer exposure experiments of DMF vapor in laboratories, the proportions of the skin absorption to the total absorption were reported to be 14-39%1), 13-39%2), and 22-70%3). However, it may not be appropriate to simply extrapolate these results to the working population, because working conditions influencing DMF vapor absorption, for example, temperature, humidity, physical activity, etc., are quite different from those of the volunteer laboratory exposure experiments. This study aimed to clarify the significance of the skin absorption of DMF vapor at worksites.

Original languageEnglish
Pages (from-to)92-94
Number of pages3
JournalJournal of occupational health
Issue number2
Publication statusPublished - 2001


  • Biological monitoring
  • N,N-Dimethylformamide
  • N-Methylformamide
  • Skin absorption
  • Volunteer

ASJC Scopus subject areas

  • General Medicine


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