Noninvasive blood glucose monitoring system

Makoto Kikuchi, Shinsuke Kayashima, Tsunenori Arai, Naokazu Nagata, Akio Kaneyoshi, Shio Shinohara, Narushi Ito

Research output: Contribution to journalArticlepeer-review


A novel noninvasive and quasi-continuous method of transcutaneous blood glucose monitoring system has been developed. The constituents of effuse transcutaneous fluid, suction effusion fluid (SEF) was analyzed, and its glucose concentration during glucose loading in rabbits and patients was monitored. A 75 g oral glucose tolerance test (OGTT) was also carried out with volunteers with impaired glucose tolerance. The subject suffered mild skin damage with slight redness and slight skin irritation without subcutaneous hemorrhage after the suction procedure was applied for about six hours. A small and wearable apparatus based on this prototype system was also developed.

Original languageEnglish
Pages (from-to)840-846
Number of pages7
JournalBiomedical Engineering - Applications, Basis and Communications
Issue number6
Publication statusPublished - 1994 Jan 1

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomedical Engineering


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