TY - JOUR
T1 - Novel monoterpene lactones from Cinnamomum inunctum
AU - Fuchino, Hiroyuki
AU - Yazawa, Aya
AU - Kiuchi, Fumiyuki
AU - Kawahara, Nobuo
AU - Takahashi, Yutaka
AU - Satake, Motoyoshi
N1 - Publisher Copyright:
© 2015 The Pharmaceutical Society of Japan.
PY - 2015/10/1
Y1 - 2015/10/1
N2 - Four new monoterpene lactones, 5-(2,3-dihydroxy-3-methylbutyl)-4-hydroxy-4-methyldihydrofuran-2(3H)-one (1), 5-(2,3-dihydroxy-3-methylbutyl)-4-methylfuran-2(5H)-one (2), 8-hydroxy-4,7,7-trimethyl-1,6-dioxaspiro[4.4]non-3-en-2-one (3) and 8-hydroxy-4,7,7-trimethyl-1,6-dioxaspiro[4.4]non-3-en-2-one (4), were isolated from the methanolic extract of the fruit of Cinnamomum inunctum, a folk medicine in Myanmar, together with a known compound, 3-hydroxy-4,4-dimethyl-4-butyrolactone (5). Their chemical structures were determined by spectral methods. Among these, 3 and 4 possessed unique spirolactone moieties.
AB - Four new monoterpene lactones, 5-(2,3-dihydroxy-3-methylbutyl)-4-hydroxy-4-methyldihydrofuran-2(3H)-one (1), 5-(2,3-dihydroxy-3-methylbutyl)-4-methylfuran-2(5H)-one (2), 8-hydroxy-4,7,7-trimethyl-1,6-dioxaspiro[4.4]non-3-en-2-one (3) and 8-hydroxy-4,7,7-trimethyl-1,6-dioxaspiro[4.4]non-3-en-2-one (4), were isolated from the methanolic extract of the fruit of Cinnamomum inunctum, a folk medicine in Myanmar, together with a known compound, 3-hydroxy-4,4-dimethyl-4-butyrolactone (5). Their chemical structures were determined by spectral methods. Among these, 3 and 4 possessed unique spirolactone moieties.
KW - Cinnamomum inunctum
KW - Lauraceae
KW - Monoterpene
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U2 - 10.1248/cpb.c15-00368
DO - 10.1248/cpb.c15-00368
M3 - Article
C2 - 26423041
AN - SCOPUS:84947566132
SN - 0009-2363
VL - 63
SP - 833
EP - 836
JO - Chemical and Pharmaceutical Bulletin
JF - Chemical and Pharmaceutical Bulletin
IS - 10
ER -